Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry

Patrick J. Keeling; Hans Peter Klenk; Rama K. Singh; Margret E. Schenk; Christoph W. Sensen; Wolfram Zillig; W. Ford Doolittle

doi:10.1007/s007920050083

Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry

Patrick J. Keeling, Hans Peter Klenk, Rama K. Singh, Margret E. Schenk, Christoph W. Sensen, Wolfram Zillig, W. Ford Doolittle

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

The complete sequence of the plasmid pRN2 from the thermoacidophile Sulfolobus islandicus has been determined. The plasmid was found to be circular and 6959bp in length. S. islandicus harbors another endogenous plasmid, pRN1, and comparison of pRN1 and pRN2 revealed that these two plasmids are essentially homologous, although very distantly related. pRN1 and pRN2 share several stretches of highly conserved noncoding DNA and three common open reading frames. Two of these reading frames are likely related to replication, one encoding a large protein with a helicase domain similar to viral helicases, and the other a copy number control protein, CopG.

Original language	English
Pages (from-to)	391-393
Number of pages	3
Journal	Extremophiles
Volume	2
Issue number	4
DOIs	https://doi.org/10.1007/s007920050083
Publication status	Published - Nov 1998

Bibliographical note

Funding Information:
Acknowledgments This project was funded by the Canadian Genome Analysis and Technology program, and a grant to W.F.D. from the Medical Research Council (MRC). P.J.K. was the recipient of a MRC studentship. W.F.D. is a fellow of the Canadian Institute for Advanced Research. P.J.K. thanks G.I. McFadden for providing facilities for the preparation of this manuscript. This publication is registered as NRCC #39782 by the National Research Council of Canada. The sequence of pRN2 has been deposited in GenBank under the accession number U93082.

ASJC Scopus Subject Areas

Microbiology
Molecular Medicine

Access to Document

10.1007/s007920050083

Cite this

@article{9ad2827b3dd44cbb89bb1e6fae3ee9b5,

title = "Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry",

abstract = "The complete sequence of the plasmid pRN2 from the thermoacidophile Sulfolobus islandicus has been determined. The plasmid was found to be circular and 6959bp in length. S. islandicus harbors another endogenous plasmid, pRN1, and comparison of pRN1 and pRN2 revealed that these two plasmids are essentially homologous, although very distantly related. pRN1 and pRN2 share several stretches of highly conserved noncoding DNA and three common open reading frames. Two of these reading frames are likely related to replication, one encoding a large protein with a helicase domain similar to viral helicases, and the other a copy number control protein, CopG.",

author = "Keeling, {Patrick J.} and Klenk, {Hans Peter} and Singh, {Rama K.} and Schenk, {Margret E.} and Sensen, {Christoph W.} and Wolfram Zillig and {Ford Doolittle}, W.",

note = "Funding Information: Acknowledgments This project was funded by the Canadian Genome Analysis and Technology program, and a grant to W.F.D. from the Medical Research Council (MRC). P.J.K. was the recipient of a MRC studentship. W.F.D. is a fellow of the Canadian Institute for Advanced Research. P.J.K. thanks G.I. McFadden for providing facilities for the preparation of this manuscript. This publication is registered as NRCC #39782 by the National Research Council of Canada. The sequence of pRN2 has been deposited in GenBank under the accession number U93082.",

year = "1998",

month = nov,

doi = "10.1007/s007920050083",

language = "English",

volume = "2",

pages = "391--393",

journal = "Extremophiles",

issn = "1431-0651",

publisher = "Springer Japan",

number = "4",

}

TY - JOUR

T1 - Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry

AU - Keeling, Patrick J.

AU - Klenk, Hans Peter

AU - Singh, Rama K.

AU - Schenk, Margret E.

AU - Sensen, Christoph W.

AU - Zillig, Wolfram

AU - Ford Doolittle, W.

N1 - Funding Information: Acknowledgments This project was funded by the Canadian Genome Analysis and Technology program, and a grant to W.F.D. from the Medical Research Council (MRC). P.J.K. was the recipient of a MRC studentship. W.F.D. is a fellow of the Canadian Institute for Advanced Research. P.J.K. thanks G.I. McFadden for providing facilities for the preparation of this manuscript. This publication is registered as NRCC #39782 by the National Research Council of Canada. The sequence of pRN2 has been deposited in GenBank under the accession number U93082.

PY - 1998/11

Y1 - 1998/11

N2 - The complete sequence of the plasmid pRN2 from the thermoacidophile Sulfolobus islandicus has been determined. The plasmid was found to be circular and 6959bp in length. S. islandicus harbors another endogenous plasmid, pRN1, and comparison of pRN1 and pRN2 revealed that these two plasmids are essentially homologous, although very distantly related. pRN1 and pRN2 share several stretches of highly conserved noncoding DNA and three common open reading frames. Two of these reading frames are likely related to replication, one encoding a large protein with a helicase domain similar to viral helicases, and the other a copy number control protein, CopG.

AB - The complete sequence of the plasmid pRN2 from the thermoacidophile Sulfolobus islandicus has been determined. The plasmid was found to be circular and 6959bp in length. S. islandicus harbors another endogenous plasmid, pRN1, and comparison of pRN1 and pRN2 revealed that these two plasmids are essentially homologous, although very distantly related. pRN1 and pRN2 share several stretches of highly conserved noncoding DNA and three common open reading frames. Two of these reading frames are likely related to replication, one encoding a large protein with a helicase domain similar to viral helicases, and the other a copy number control protein, CopG.

UR - http://www.scopus.com/inward/record.url?scp=0032211967&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032211967&partnerID=8YFLogxK

U2 - 10.1007/s007920050083

DO - 10.1007/s007920050083

M3 - Article

C2 - 9827327

AN - SCOPUS:0032211967

SN - 1431-0651

VL - 2

SP - 391

EP - 393

JO - Extremophiles

JF - Extremophiles

IS - 4

ER -

Sulfolobus islandicus plasmids pRN1 and pRN2 share distant but common evolutionary ancestry

Abstract

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this