Abstract
Objective: Increases in postpartum hemorrhage have been reported from several countries. We assessed temporal trends in postpartum hemorrhage and severe postpartum hemorrhage in Canada between 2003 and 2010. Methods: We carried out a population-based cohort study of all hospital deliveries in Canada (excluding Quebec) from 2003 to 2010 (n. =. 2 193 425), using data from the Canadian Institute for Health Information. Postpartum hemorrhage was defined as a blood loss of ≥ 500 mL following vaginal delivery or ≥ 1000 mL following Caesarean section, or as noted by the care provider. Severe postpartum hemorrhage was defined as postpartum hemorrhage plus blood transfusion, hysterectomy, or other procedures to control bleeding (including uterine suturing or ligation/embolization of pelvic arteries). Temporal trends were assessed using the chi-square test for trend, relative risks, and logistic regression. Results: Postpartum hemorrhage increased by 22% (95% CI 20% to 25%) from 5.1% in 2003 to 6.2% in 2010 (P < 0.001), driven by a 29% increase (95% CI 26% to 33%) in atonic postpartum hemorrhage (3.9% in 2003 vs. 5.0% in 2010, P < 0.001). Postpartum hemorrhage with blood transfusion increased from 36.7 to 50.4 per 10 000 deliveries (P < 0.001), while postpartum hemorrhage with hysterectomy increased from 4.9 to 5.8 per 10 000 deliveries (P < 0.01). Postpartum hemorrhage with uterine suturing, or ligation/embolization of pelvic arteries, increased from 4.1 to 10.7 per 10 000 deliveries (P < 0.001). These increases occurred in most provinces and territories, and could not be explained by changes in maternal, fetal, and obstetric factors. Conclusion: Rates of postpartum hemorrhage and severe postpartum hemorrhage continued to increase in Canada between 2003 and 2010.
Original language | English |
---|---|
Pages (from-to) | 21-33 |
Number of pages | 13 |
Journal | Journal of Obstetrics and Gynaecology Canada |
Volume | 36 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |
Bibliographical note
Funding Information:Azar Mehrabadi is supported by a Canadian Institutes of Health Research Team grant in Severe Maternal Morbidity (MAH—115445). Jennifer A. Hutcheon is the recipient of a New Investigator Award from the Canadian Institutes of Health Research and a Scholar Award from the Michael Smith Foundation for Health Research. K.S. Joseph is supported by the Child and Family Research Institute and holds a Chair in maternal, fetal, and infant health services research from the Canadian Institutes of Health Research.
Publisher Copyright:
© 2014 Society of Obstetricians and Gynaecologists of Canada.
ASJC Scopus Subject Areas
- Obstetrics and Gynaecology
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't