Abstract
Human preadipocytes contain nuclear factors that specifically bind to the AE-1 sequence, previously demonstrated as an enhancer element in the regulation of adipose P2 gene expression during 3T3 adipose differentiation. By transient transfection and in vivo competition experiments, the trans-acting factors were found to bind either to the C/EBP recognition site in the AE-1 sequence and act as a negative regulator or to the adjacent site (termed 3′ AE-1) and act as a positive regulator of adipose P2 gene activity in human preadipocytes.
| Original language | English |
|---|---|
| Pages (from-to) | 2303-2306 |
| Number of pages | 4 |
| Journal | Molecular and Cellular Biology |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1991 |
ASJC Scopus Subject Areas
- Molecular Biology
- Cell Biology
Fingerprint
Dive into the research topics of 'The C/EBP-Binding Region and Adjacent Sites Regulate Expression of the Adipose P2 Gene in Human Preadipocytes'. Together they form a unique fingerprint.Cite this
Ro, H. S., & Roncari, D. A. K. (1991). The C/EBP-Binding Region and Adjacent Sites Regulate Expression of the Adipose P2 Gene in Human Preadipocytes. Molecular and Cellular Biology, 11(4), 2303-2306. https://doi.org/10.1128/MCB.11.4.2303