Abstract
The anticonvulsant activity of apomorphine, (+)‐amphetamine and pargyline + l‐dopa was examined in the rat and mouse. Whereas all three treatments produced anticonvulsant effects in the rat, only (+)‐amphetamine and l‐dopa were anticonvulsant in the mouse. It is suggested that enhanced dopamine‐like activity is responsible for the anticonvulsant activity of these three drugs in the rat. The anticonvulsant activity of (+)‐amphetamine and l‐dopa in the mouse may be unrelated to their pharmacological activity on dopaminergic neurons. 1972 Royal Pharmaceutical Society of Great Britain
| Original language | English |
|---|---|
| Pages (from-to) | 696-701 |
| Number of pages | 6 |
| Journal | Journal of Pharmacy and Pharmacology |
| Volume | 24 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Sept 1972 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Pharmacology
- Pharmaceutical Science
PubMed: MeSH publication types
- Journal Article