The mortality rate as a function of accumulated deficits in a frailty index

Arnold B. Mitnitski; Alexander J. Mogilner; Chris MacKnight; Kenneth Rockwood

doi:10.1016/S0047-6374(02)00082-9

The mortality rate as a function of accumulated deficits in a frailty index

Arnold B. Mitnitski, Alexander J. Mogilner, Chris MacKnight, Kenneth Rockwood

Research output: Contribution to journal › Article › peer-review

206 Citations (Scopus)

Abstract

In a representative Canadian population survey (n=66 589) the proportion of accumulated deficits in a frailty index showed a linear relationship with mortality in a log-log plot, such that the mortality rate was a power-law function of the frailty index. Represented in this way, the frailty index readily summarizes individual differences in health status. The exponent and amplitude parameters of the power function are gender specific, reflecting that while, on average, women accumulate more deficits than men of the same age, their risk of mortality is lower. The dependence of the mortality rate on the frailty index points to the merit of the index as a simple and accessible tool for estimating individual risks of mortality.

Original language	English
Pages (from-to)	1457-1460
Number of pages	4
Journal	Mechanisms of Ageing and Development
Volume	123
Issue number	11
DOIs	https://doi.org/10.1016/S0047-6374(02)00082-9
Publication status	Published - Sept 2002

Bibliographical note

Funding Information:
This analysis was funded by Health Canada through the National Health Research and Development Program, Grant #6603-03-1999/2640043. Chris MacKnight is supported by a New Investigator Award and Kenneth Rockwood by an Investigator Award from the Canadian Institutes of Health Research. Kenneth Rockwood is also supported by the Dalhousie Medical Research Foundation as the Kathryn Allen Weldon Professor of Alzheimer Research. The views expressed herein do not necessarily represent the official policy of Health Canada. The authors gratefully acknowledge two anonymous referees for their comments.

ASJC Scopus Subject Areas

Ageing
Developmental Biology

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10.1016/S0047-6374(02)00082-9

Cite this

Mitnitski, A. B., Mogilner, A. J., MacKnight, C., & Rockwood, K. (2002). The mortality rate as a function of accumulated deficits in a frailty index. Mechanisms of Ageing and Development, 123(11), 1457-1460. https://doi.org/10.1016/S0047-6374(02)00082-9

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abstract = "In a representative Canadian population survey (n=66 589) the proportion of accumulated deficits in a frailty index showed a linear relationship with mortality in a log-log plot, such that the mortality rate was a power-law function of the frailty index. Represented in this way, the frailty index readily summarizes individual differences in health status. The exponent and amplitude parameters of the power function are gender specific, reflecting that while, on average, women accumulate more deficits than men of the same age, their risk of mortality is lower. The dependence of the mortality rate on the frailty index points to the merit of the index as a simple and accessible tool for estimating individual risks of mortality.",

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The mortality rate as a function of accumulated deficits in a frailty index

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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