Abstract
The Nuclear Protein Database (NPD) is a curated database that contains information on more than 1300 vertebrate proteins that are thought, or are known, to localise to the cell nucleus. Each entry is annotated with information on predicted protein size and isoelectric point, as well as any repeats, motifs or domains within the protein sequence. In addition, information on the sub-nuclear localisation of each protein is provided and the biological and molecular functions are described using Gene Ontology (GO) terms. The database is searchable by keyword, protein name, sub-nuclear compartment and protein domain/motif. Links to other databases are provided (e.g. Entrez, SWISS-PROT, OMIM, PubMed, PubMed Central). Thus, NPD provides a gateway through which the nuclear proteome may be explored. The database can be accessed at http://npd.hgu.mrc. ac.uk and is updated monthly.
| Original language | English |
|---|---|
| Pages (from-to) | 328-330 |
| Number of pages | 3 |
| Journal | Nucleic Acids Research |
| Volume | 31 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2003 |
| Externally published | Yes |
Bibliographical note
Funding Information:We would like to acknowledge the help of MRC HGU computing services and Dr Heidi Sutherland for comments and data entry during the development of NPD. We especially thank all colleagues who have contributed to the development and information content of NPD. The NPD was made possible by funding from the Medical Research Council (UK) and the James S. McDonnell Foundation. G.D. was supported by a fellowship from the Canadian Institutes of Health Research (CIHR) and W.A.B. is a Centennial Fellow of the James S. McDonnell Foundation.
ASJC Scopus Subject Areas
- Genetics