Abstract
Mouse spleen cells which are synthesizing IgE can sensitize rat skin for HACA. When such cells are treated with mouse interferon, their ability to sensitize rat skin is reduced or completely inhibited. Two hundred PRD50 units of interferon reduced HACA reactions by more than 50%; 600 units gave complete inhibition. Interferon may act by inhibiting IgE synthesis and/or release.
Original language | English |
---|---|
Pages (from-to) | 1063-1066 |
Number of pages | 4 |
Journal | Journal of Immunology |
Volume | 117 |
Issue number | 4 |
Publication status | Published - 1976 |
ASJC Scopus Subject Areas
- Immunology and Allergy
- Immunology
Fingerprint
Dive into the research topics of 'The suppressive effect of interferon on the ability of mouse spleen cells synthesizing IgE to sensitize rat skin for heterologous adoptive cutaneous anaphylaxis'. Together they form a unique fingerprint.Cite this
Ngan, J., Lee, S. H. S., & Kind, L. S. (1976). The suppressive effect of interferon on the ability of mouse spleen cells synthesizing IgE to sensitize rat skin for heterologous adoptive cutaneous anaphylaxis. Journal of Immunology, 117(4), 1063-1066.