Toward a tissue-engineered heart: Defining collagen structure/function relations in load-bearing cardiac structures

A. R. Jahangir, J. M. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The collagen structure/function relations in load-bearing cardiac structures were discussed. A dynamic hydrothermal isometric tension (DHIT) apparatus was used to examine collagen in various cardiac tissues such as bovine left-side and right-side chordae tendineae (CT), aortic valve and mitral valve leaflets. The right-side (R-CT) and left-side (L-CT) chordae were exercised from the right or left ventricular cavities with a mean length of 20 nm and a mean original unloaded diameter of 1.05 mm. It was observed that the location and function of cardiac, collageneous tissues were the main parameters that decide the structural features of the tissues.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages576
Number of pages1
Publication statusPublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus Subject Areas

  • General Engineering

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