Translating Delirium Prevention Strategies for Elderly Adults with Hip Fracture into Routine Clinical Care: A Pragmatic Clinical Trial

Susan Freter, Katalin Koller, Michael Dunbar, Chris MacKnight, Kenneth Rockwood

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Objectives: To compare the feasibility (adherence) and effectiveness (prevalence of delirium, length of stay, mortality, discharge site) of delirium-friendly preprinted postoperative orders (PPOs) for individuals with hip fracture, administered by regular orthopedic nurses, with routine postoperative orders. Design: Pragmatic clinical trial to evaluate a quality improvement intervention. Setting: Tertiary care hospital. Participants: Individuals aged 65 and older admitted for hip fracture repair (N = 283). Intervention: PPOs with delirium-friendly options and doses for nighttime sedation, analgesia, and nausea and attention to catheter removal and bowel movements. Measurements: Adherence to PPO was compared with adherence to routine orders. Drug doses were recorded. Presence of delirium was documented using the Confusion Assessment Method and the Mini-Mental State Examination on postoperative Days 1, 3, and 5. Length of stay, discharge site, and in-hospital mortality were recorded. Results: Orthopedic nurses adhered reasonably well with delirium-friendly PPOs. Of 283 participants, 42% developed postoperative delirium, with significantly less delirium in the intervention group (intervention 33%, control 51%, P =.001). The effect of the intervention was stronger in individuals with preexisting dementia (intervention 60%, control 97%, P <.001). Participants with postoperative delirium had longer hospital stays and were more likely to die or be discharged to a nursing home, but there was no significant between-group difference in these outcomes. Conclusion: It is possible to introduce delirium-friendly PPOs into routine post-hip fracture care in a representative elderly population including individuals with dementia. Delirium-friendly PPOs executed by regular nursing staff resulted in a significant reduction in postoperative delirium but no difference in other outcomes.

Original languageEnglish
Pages (from-to)567-573
Number of pages7
JournalJournal of the American Geriatrics Society
Volume65
Issue number3
DOIs
Publication statusPublished - Mar 1 2017

Bibliographical note

Funding Information:
The authors would like to acknowledge Jane Storey for her tireless enthusiasm in preparing the manuscript for ethics approval and grant application and Gwen Dobbin for her efforts in data collection and study coordination. This work was supported by Nova Scotia Health Research Foundation Grant D2006–46 and the Capital Health Research Fund. Conflict of Interest: None. Author Contributions: Freter: study concept and design, acquisition of subjects and data, analysis and interpretation of data, preparation of manuscript. Dunbar, MacKnight, Rockwood: study concept and design, interpretation of data, preparation of manuscript. Koller: study concept and design, acquisition of subjects and data, preparation of manuscript. Sponsor's Role: The sponsors had no direct role in the design, methods, subject recruitment, data collections, analysis, or preparation of the manuscript.

Publisher Copyright:
© 2016 The Authors. The Journal of the American Geriatrics Society published by Wiley Periodicals, Inc. on behalf of The American Geriatrics Society.

ASJC Scopus Subject Areas

  • Geriatrics and Gerontology

PubMed: MeSH publication types

  • Journal Article
  • Pragmatic Clinical Trial

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