Value and limitations of an inverse solution for two equivalent dipoles in localising dual accessory pathways

Investigations were carried out into whether an equivalent generator consisting of two dipoles could be used to detect dual sites of ventricular activity. A computer model of the human ventricular myocardium was used to simulate activation sequences initiated at eight different pairs of sites positioned on the epicardial surface of the atrio-ventricular ring. From these sequences, 117-lead body surface potentials (covering the anterior and posterior torso), 64-lead magnetic field maps (above the anterior chest) and 128-lead magnetic field maps (above the anterior and posterior chest) were simulated and were then used to localise dual accessory pathways employing pairs of equivalent dipoles. Average localisation errors were 12mm, 12mm and 9mm, respectively, when body surface potentials, 64-lead and 128-lead magnetic fields were used. The results of the study suggest that solving the inverse problem for two dipoles could provide additional information on dual accessory pathways prior to electrophysiological study.