Resumen
Prior to their announcement of the birth of gene-edited twins in China, Dr. He Jiankui and colleagues published a set of draft ethical principles for discussing the legal, social, and ethical aspects of heritable genome interventions. Within this document, He and colleagues made it clear that their goal with these principles was to “clarify for the public the clinical future of early-in-life genetic surgeries” or heritable genome editing. In light of He’s widely criticized gene editing experiments it is of interest to place these draft principles in the larger ethical debate surrounding heritable genome editing. Here we examine the principles proposed by He and colleagues through the lens of Beauchamp and Childress’ Principles of Biomedical Ethics. We also analyze the stated goal that the “clinical future” of heritable genome editing was clarified by He and colleagues’ proposed principles. Finally, we highlight what might be done to help prevent individual actors from pushing forward ahead of broad societal consensus on heritable genome editing.
Idioma original | English |
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Páginas (desde-hasta) | 2735-2748 |
Número de páginas | 14 |
Publicación | Science and Engineering Ethics |
Volumen | 26 |
N.º | 5 |
DOI | |
Estado | Published - oct. 1 2020 |
Nota bibliográfica
Funding Information:G.D. is funded for research involving CRISPR technologies by a Project Grant (PJT-156017) from the Canadian Institutes of Health Research (CIHR) and L.J.G. is supported by the Vanier Canadian Graduate Scholarship program through the Natural Sciences and Engineering Research Council of Canada (NSERC). We would also like to thank Dr. Françoise Baylis and Dr. Natalie Kofler for many clarifying and insightful conversations.
Publisher Copyright:
© 2020, Springer Nature B.V.
ASJC Scopus Subject Areas
- Health(social science)
- Issues, ethics and legal aspects
- Health Policy
- Management of Technology and Innovation