Cell-free screening for Nox inhibitors

Karen Bedard; Vincent Jaquet

doi:10.1016/j.chembiol.2012.06.002

Cell-free screening for Nox inhibitors

Karen Bedard, Vincent Jaquet

Medicine

Medicine

Producción científica: Contribución a una revista › Encuesta corta › revisión exhaustiva

3 Citas (Scopus)

Resumen

NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.

Idioma original	English
Páginas (desde-hasta)	664-665
Número de páginas	2
Publicación	Chemistry and Biology
Volumen	19
N.º	6
DOI	https://doi.org/10.1016/j.chembiol.2012.06.002
Estado	Published - jun. 22 2012

ASJC Scopus Subject Areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmacology
Drug Discovery
Clinical Biochemistry

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10.1016/j.chembiol.2012.06.002

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@article{30c5a276d8e24dbf9eafb7ba7c0632a1,

title = "Cell-free screening for Nox inhibitors",

abstract = "NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.",

author = "Karen Bedard and Vincent Jaquet",

year = "2012",

month = jun,

day = "22",

doi = "10.1016/j.chembiol.2012.06.002",

language = "English",

volume = "19",

pages = "664--665",

journal = "Chemistry and Biology",

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number = "6",

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T1 - Cell-free screening for Nox inhibitors

AU - Bedard, Karen

AU - Jaquet, Vincent

PY - 2012/6/22

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N2 - NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.

AB - NOX enzymes are major ROS generators in pathological states and represent a promising pharmacological target. In this issue of Chemistry & Biology, Smith and colleagues developed an original and elegant cell-free assay to identify specific Nox2 inhibitors in a high throughput manner.

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U2 - 10.1016/j.chembiol.2012.06.002

DO - 10.1016/j.chembiol.2012.06.002

M3 - Short survey

AN - SCOPUS:84862726472

SN - 1074-5521

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JO - Chemistry and Biology

JF - Chemistry and Biology

IS - 6

ER -

Cell-free screening for Nox inhibitors

Resumen

ASJC Scopus Subject Areas

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