TY - JOUR
T1 - CHARGE and esophageal atresia
AU - Kutiyanawala, M.
AU - Wyse, R. K.H.
AU - Brereton, R. J.
AU - Spitz, L.
AU - Kiely, E. M.
AU - Drake, D.
AU - Blake, K.
PY - 1992/5
Y1 - 1992/5
N2 - CHARGE association was diagnosed in 61 infants, 20 of whom died, mainly during the first 2 years of life. Esophageal atresia and/or tracheoesophageal fistula were present in 10 neonates. Axial skeletal anomalies occurred in 7 of the 10, but none had preaxial limb defects typical of the VATER association. All had major cardiac anomalies, predominantly tetralogy of Fallot. The majority of patients had primary repair of the esophagus. The postoperative course was stormy in all patients, with a high incidence of complications and 70% died. The recognition of features of the CHARGE association is important because it has major prognostic and therapeutic implications.
AB - CHARGE association was diagnosed in 61 infants, 20 of whom died, mainly during the first 2 years of life. Esophageal atresia and/or tracheoesophageal fistula were present in 10 neonates. Axial skeletal anomalies occurred in 7 of the 10, but none had preaxial limb defects typical of the VATER association. All had major cardiac anomalies, predominantly tetralogy of Fallot. The majority of patients had primary repair of the esophagus. The postoperative course was stormy in all patients, with a high incidence of complications and 70% died. The recognition of features of the CHARGE association is important because it has major prognostic and therapeutic implications.
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U2 - 10.1016/0022-3468(92)90445-D
DO - 10.1016/0022-3468(92)90445-D
M3 - Article
C2 - 1625119
AN - SCOPUS:0026647729
SN - 0022-3468
VL - 27
SP - 558
EP - 560
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 5
ER -