TY - CHAP
T1 - Detecting and rating dementia of Alzheimer type through lexical analysis of spontaneous speech
AU - Thomas, Calvin
AU - Kešelj, Vlado
AU - Cercone, Nick
AU - Rockwood, Kenneth
AU - Asp, Elissa
PY - 2013
Y1 - 2013
N2 - Current methods of assessing dementia of Alzheimer type (DAT) rely on structured interviews, which attempt to capture the complex nature of deficits suffered. One of the most significant areas affected by the disease is the capacity for functional communication as linguistic skills break down. These methods often do not capture the true nature of language deficits in spontaneous speech. This issue is addressed by exploring novel automatic and objective methods for diagnosing patients through analysis of spontaneous speech. We detail several lexical approaches to the problem of detecting and rating DAT. The approaches explored rely on character n-gram-based techniques, which are shown to perform successfully in a different, but related task of automatic authorship attribution. We also explore the correlation of usage frequency of different parts of speech and DAT. We achieve a high 95% accuracy of detecting dementia when compared with a control group, we achieve 70% accuracy in rating dementia in two classes, and 50% accuracy in rating dementia into four classes. These results show that purely computational solutions offer a viable alternative to standard approaches to diagnosing the level of impairment in patients, and they present a significant step forward toward automatic and objective means to identifying early symptoms of DAT in older adults.
AB - Current methods of assessing dementia of Alzheimer type (DAT) rely on structured interviews, which attempt to capture the complex nature of deficits suffered. One of the most significant areas affected by the disease is the capacity for functional communication as linguistic skills break down. These methods often do not capture the true nature of language deficits in spontaneous speech. This issue is addressed by exploring novel automatic and objective methods for diagnosing patients through analysis of spontaneous speech. We detail several lexical approaches to the problem of detecting and rating DAT. The approaches explored rely on character n-gram-based techniques, which are shown to perform successfully in a different, but related task of automatic authorship attribution. We also explore the correlation of usage frequency of different parts of speech and DAT. We achieve a high 95% accuracy of detecting dementia when compared with a control group, we achieve 70% accuracy in rating dementia in two classes, and 50% accuracy in rating dementia into four classes. These results show that purely computational solutions offer a viable alternative to standard approaches to diagnosing the level of impairment in patients, and they present a significant step forward toward automatic and objective means to identifying early symptoms of DAT in older adults.
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U2 - 10.3233/978-1-61499-258-5-154
DO - 10.3233/978-1-61499-258-5-154
M3 - Chapter
AN - SCOPUS:84894543729
SN - 9781614992578
T3 - Frontiers in Artificial Intelligence and Applications
SP - 154
EP - 171
BT - Computational Approaches to Assistive Technologies for People with Disabilities
A2 - Cercone, Nick
A2 - Naruedomkul, Kanlaya
ER -