Elevated blood lead levels among children living in a fishing community, Karachi, Pakistan

Siroos Hozhabri; Franklin White; Mohammad Hossein Rahbar; Mubina Agboatwalla; Stephen Luby

doi:10.3200/AEOH.59.1.37-41

Elevated blood lead levels among children living in a fishing community, Karachi, Pakistan

Siroos Hozhabri, Franklin White, Mohammad Hossein Rahbar, Mubina Agboatwalla, Stephen Luby

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14 Citas (Scopus)

Resumen

Lead is a widespread environmental contaminant worldwide and is associated with adverse outcomes in children, including impaired neurobehavioral development and learning difficulties. A cross-sectional survey of 53 young children was conducted in a fishing village on an island adjacent to Karachi, Pakistan. Whole blood from each individual was tested for lead levels. Also tested were samples of cooked food, house dust, and drinking water from 36 households. Laboratory determinations were made by the Pakistan Council for Scientific and Industrial Research with quality control by the United States Centers for Disease Control and Prevention. Fifty-two subjects (98%) had blood lead levels above 10 μg/dl (mean 21.60 pg/dl), an internationally recognized threshold for potential neurotoxicity. The mean concentration was 3.90 μg/g in cooked food, 4.02 μg/l in drinking water, and 91.30 μg/g in house dust. These findings indicate possible major health concerns and suggest significant environmental contamination in this community as well as the need to identify locally relevant early childhood exposures.

Idioma original	English
Páginas (desde-hasta)	37-41
Número de páginas	5
Publicación	Archives of Environmental Health
Volumen	59
N.º	1
DOI	https://doi.org/10.3200/AEOH.59.1.37-41
Estado	Published - ene. 2004
Publicado de forma externa	Sí

Nota bibliográfica

Funding Information:
We are grateful to the Eastern Mediterranean Office of the World Health Organization for funding this study. PCSIR performed the lead analysis under contract. We acknowledge the assistance of the lead branch of the Centers for Disease Control and Prevention in standardization of the PCSIR laboratory’s generous analysis of the blood samples. The first author’s post as research fellow during the conduct of this study was supported in part by a grant to support international training and research in environmental health from the Fogarty International Center of the U.S. National Institutes of Health, administered by the University of Alabama at Birmingham, in collaboration with the Aga Khan University.

ASJC Scopus Subject Areas

Environmental Chemistry
General Environmental Science
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

PubMed: MeSH publication types

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

ODS de las Naciones Unidas

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abstract = "Lead is a widespread environmental contaminant worldwide and is associated with adverse outcomes in children, including impaired neurobehavioral development and learning difficulties. A cross-sectional survey of 53 young children was conducted in a fishing village on an island adjacent to Karachi, Pakistan. Whole blood from each individual was tested for lead levels. Also tested were samples of cooked food, house dust, and drinking water from 36 households. Laboratory determinations were made by the Pakistan Council for Scientific and Industrial Research with quality control by the United States Centers for Disease Control and Prevention. Fifty-two subjects (98%) had blood lead levels above 10 μg/dl (mean 21.60 pg/dl), an internationally recognized threshold for potential neurotoxicity. The mean concentration was 3.90 μg/g in cooked food, 4.02 μg/l in drinking water, and 91.30 μg/g in house dust. These findings indicate possible major health concerns and suggest significant environmental contamination in this community as well as the need to identify locally relevant early childhood exposures.",

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Elevated blood lead levels among children living in a fishing community, Karachi, Pakistan

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

PubMed: MeSH publication types

ODS de las Naciones Unidas

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