External Validation of the Patient-Reported Villalta Scale for the Diagnosis of Postthrombotic Syndrome

Sara Ng, Marc A. Rodger, Waleed Ghanima, Michael J. Kovacs, Sudeep Shivakumar, Susan R. Kahn, Per Morten Sandset, Clive Kearon, Ranjeeta Mallick, Aurélien Delluc

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

6 Citas (Scopus)

Resumen

INTRODUCTION:  The Villalta scale is the endorsed tool to diagnose and grade the severity of postthrombotic syndrome (PTS); however, assessing presence and severity of PTS is time-consuming and relies on both the clinician and patient's assessments. The patient-reported Villalta scale version 2 (PRV2) is a visually assisted form that enables patients to self-assess presence and severity of PTS. Herein, we report on external validation of this tool. METHODS:  We assessed the agreement and kappa values of PRV2 to diagnose and assess severity of PTS compared with the original Villalta score in a cohort of 181 patients (196 limbs) who participated in the SAVER pilot randomized control trial. Presence of PTS was defined as PRV2 ≥5 or a Villalta score ≥5. RESULTS:  PTS prevalence was 42% using PRV2 and 33% using the Villalta scale. The corresponding kappa and percentage agreement were 0.60 (95% confidence interval [CI]: 0.49-0.71) and 81% (95% CI: 76-87), respectively. Kappa values and percentage agreements between PRV2 and Villalta scale increased with increasing severity of PTS. The sensitivity of PRV2 to detect PTS of any severity was 84% (95% CI: 73-92) with a specificity of 79% (95% CI: 71-86). CONCLUSION:  We conclude that the PRV2 is an acceptable tool for diagnosing and grading the severity of PTS.

Idioma originalEnglish
Páginas (desde-hasta)1379-1383
Número de páginas5
PublicaciónThrombosis and Haemostasis
Volumen122
N.º8
DOI
EstadoPublished - ago. 1 2022
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
Thieme. All rights reserved.

ASJC Scopus Subject Areas

  • Hematology

PubMed: MeSH publication types

  • Journal Article
  • Randomized Controlled Trial

Huella

Profundice en los temas de investigación de 'External Validation of the Patient-Reported Villalta Scale for the Diagnosis of Postthrombotic Syndrome'. En conjunto forman una huella única.

Citar esto