Factors affecting drug biotransformation

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37 Citas (Scopus)

Resumen

Biotransformation of drugs to polar metabolites is a key step in the termination of action and the elimination of drugs used in therapeutics. A large number of factors, including infection, alter the basal rates of drug metabolism and cause a number of untoward effects and drug interactions. Although a number of techniques have been attempted, there appears to be no easy way to determine the capacity of an individual to metabolize a specific drug and to tailor drug dosage to that individual.

Idioma originalEnglish
Páginas (desde-hasta)72-75
Número de páginas4
PublicaciónClinical Biochemistry
Volumen19
N.º2
DOI
EstadoPublished - abr. 1986

Nota bibliográfica

Funding Information:
This research is supported by a grant from the Medical Research Council of Canada.

ASJC Scopus Subject Areas

  • Clinical Biochemistry

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