Resumen
Biotransformation of drugs to polar metabolites is a key step in the termination of action and the elimination of drugs used in therapeutics. A large number of factors, including infection, alter the basal rates of drug metabolism and cause a number of untoward effects and drug interactions. Although a number of techniques have been attempted, there appears to be no easy way to determine the capacity of an individual to metabolize a specific drug and to tailor drug dosage to that individual.
Idioma original | English |
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Páginas (desde-hasta) | 72-75 |
Número de páginas | 4 |
Publicación | Clinical Biochemistry |
Volumen | 19 |
N.º | 2 |
DOI | |
Estado | Published - abr. 1986 |
Nota bibliográfica
Funding Information:This research is supported by a grant from the Medical Research Council of Canada.
ASJC Scopus Subject Areas
- Clinical Biochemistry