Resumen
Background and aims: Relatively little is known about how region of residence influences frailty of seniors. Frailty indexes can be used to investigate these effects. We constructed and validated a frailty index, to investigate the differences in health status between rural and urban seniors. Methods: We studied rural (n=949) and urban (n=7598) older adults in the Canadian Study of Health and Aging, of whom 22% died over 72 months. The frailty index was generated from 40 self reported health deficits (symptoms, diseases, disabilities, unfavourable living conditions). Results: The average value of the frailty index increased exponentially with age in both groups (rural: r=0.94; urban: r=0.97, p<0.01) and was highly correlated with mortality (r=0.96 for rural, r=0.97 for urban, p<0.01). Up to age 80, there were few rural-urban differences in frailty. After age 80, the rural sample showed higher mortality than the urban sample. The hazard ratio for death for each increment in the frailty index was 1.38 (1.14-1.72) in rural participants vs 1.18 (1.11-1.26) in urban participants. Women lived longer than men at any index value. Conclusions: Frailty index analysis readily summarizes health and mortality differences between very old rural and urban dwellers, which reflect differences in deficit accumulation, and in the impact of gender on survival. The frailty index provides efficient dimensionality reduction for studying group differences in the health of older adults.
Idioma original | English |
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Páginas (desde-hasta) | 145-153 |
Número de páginas | 9 |
Publicación | Aging clinical and experimental research |
Volumen | 19 |
N.º | 2 |
DOI | |
Estado | Published - abr. 2007 |
Nota bibliográfica
Funding Information:The data reported in this article were collected as part of the Canadian Study of Health and Aging. The core study was funded through the Seniors’ Independence Research Program from the National Health Research and Development Program (NHRDP) program of Health Canada (project no. 6606-3954-MC(S)). Additional funding was provided through Pfizer Canada Incorporated through the Medical Research Council/ Pharmaceutical Manufacturers Association of Canada Health Activity Program, NHRDP (project no. 6603-1417-302(R)), Bayer Incorporated, and the British Columbia Health Research Foundation (projects no. 38(93-2) and no. 34(96-1)). The study was coordinated through the University of Ottawa and the Division of Aging and Seniors, Health Canada. Additional funds for analysis came from Hoechst Marion Roussel Canada, through a grant administered by the Medical Research Council of Canada (Grant no. MRC PA-13560). Dr. Song is supported by a post-doctoral fellowship from the Alzheimer Society of Canada. Dr. MacKnight and Professor Rockwood are both supported by investigator awards from the Canadian Institutes of Health Research. Professor Rockwood is also supported by the Kathryn Allen Weldon Chair in Alzheimer Research at Dalhousie University. Additional analytical support came from CIHR grant MOP-46169 to Dr. Mitnitski and CIHR grant RLH-54123 to Dr. MacKnight.
ASJC Scopus Subject Areas
- Ageing
- Geriatrics and Gerontology
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't