TY - JOUR
T1 - Gastrointestinal transit times of cathartics combined with charcoal
AU - Krenzelok, Edward P.
AU - Keller, Ray
AU - Stewart, Ronald D.
PY - 1985/12
Y1 - 1985/12
N2 - Oral activated charcoal usually is administered in toxic ingestions along with a cathartic. A study was done in volunteers to determine the rapidity of gastrointestinal transit when activated charcoal was administered with various cathartics. A control of activated charcoal was compared to the gastrointestinal transit times of activated charcoal plus the cathartics magnesium citrate, magnesium sulfate, or sorbitol. Activated charcoal alone produced a mean transit time of 23.5 hours; magnesium citrate catharsis occurred in 4.2 hours, magnesium sulfate catharsis occurred in 9.3 hours, and sorbitol catharsis occurred in 0.9 hours. Sorbitol clearly was the most rapidly acting cathartic.
AB - Oral activated charcoal usually is administered in toxic ingestions along with a cathartic. A study was done in volunteers to determine the rapidity of gastrointestinal transit when activated charcoal was administered with various cathartics. A control of activated charcoal was compared to the gastrointestinal transit times of activated charcoal plus the cathartics magnesium citrate, magnesium sulfate, or sorbitol. Activated charcoal alone produced a mean transit time of 23.5 hours; magnesium citrate catharsis occurred in 4.2 hours, magnesium sulfate catharsis occurred in 9.3 hours, and sorbitol catharsis occurred in 0.9 hours. Sorbitol clearly was the most rapidly acting cathartic.
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U2 - 10.1016/S0196-0644(85)81019-2
DO - 10.1016/S0196-0644(85)81019-2
M3 - Article
C2 - 4061985
AN - SCOPUS:0022400595
SN - 0196-0644
VL - 14
SP - 1152
EP - 1155
JO - Annals of Emergency Medicine
JF - Annals of Emergency Medicine
IS - 12
ER -