Genomics and the classification of mental illness: Focus on broader categories

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Resumen

Coinciding with the release of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, two recently published molecular genetics analyses suggest large overlaps in genetic liability to schizophrenia, bipolar disorder and major depressive disorder. This indicates that a broader category of severe mental illness may be an important target for future large-scale etiological and therapeutic investigations. Studies of patient groups not restricted to current diagnostic categories may lead to a genetically informed nosology.

Idioma originalEnglish
Número de artículo97
PublicaciónGenome Medicine
Volumen5
N.º10
DOI
EstadoPublished - oct. 25 2013

Nota bibliográfica

Funding Information:
RU is supported by the Canada Research Chairs program (http://www.chairs-chaires.gc.ca/) and grants from the Canadian Institutes of Health Research, the Nova Scotia Health Research Foundation and the European Commission Innovative Medicine Initiative Joint Undertaking (#115008).

Funding Information:
RU consults for the World Health Organization. He has co-chaired a steering board of a research project, unrelated to the present article, initiated and funded by Bristol Myers Squibb. RU has received no personal income from pharmaceutical or biotech industry and holds no equity in companies active in medicine, pharmaceuticals or biotechnology.

ASJC Scopus Subject Areas

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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