TY - JOUR
T1 - Giant cell carcinoma of the hypopharynx
T2 - Pathologic diagnosis and natural history
AU - Heathcote, J. Godfrey
AU - Matthews, T. Wayne
AU - Tsang, Wendy
PY - 2004/10
Y1 - 2004/10
N2 - A 48-year-old man was initially seen with a giant cell carcinoma arising in the right piriform fossa. Following debulking, the tumour was treated with chemoradiation. The patient subsequently underwent laryngopharyngectomy. Distant metastases developed 10 months following treatment, despite the absence of locoregional recurrence. To our knowledge, this is the first reported case of giant cell carcinoma of the hypopharynx and first giant cell carcinoma of the laryngopharynx treated with chemoradiation. Based on our experience, surgery should remain the primary intervention to achieve locoregional control.
AB - A 48-year-old man was initially seen with a giant cell carcinoma arising in the right piriform fossa. Following debulking, the tumour was treated with chemoradiation. The patient subsequently underwent laryngopharyngectomy. Distant metastases developed 10 months following treatment, despite the absence of locoregional recurrence. To our knowledge, this is the first reported case of giant cell carcinoma of the hypopharynx and first giant cell carcinoma of the laryngopharynx treated with chemoradiation. Based on our experience, surgery should remain the primary intervention to achieve locoregional control.
UR - http://www.scopus.com/inward/record.url?scp=16244379537&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=16244379537&partnerID=8YFLogxK
U2 - 10.2310/7070.2004.03017
DO - 10.2310/7070.2004.03017
M3 - Article
C2 - 15931820
AN - SCOPUS:16244379537
SN - 0381-6605
VL - 33
SP - 322
EP - 326
JO - Journal of Otolaryngology
JF - Journal of Otolaryngology
IS - 5
ER -