Impairments in mobility and balance in relation to frailty

Daniel H.J. Davis; Michael R.H. Rockwood; Arnold B. Mitnitski; Kenneth Rockwood

doi:10.1016/j.archger.2010.06.013

Impairments in mobility and balance in relation to frailty

Daniel H.J. Davis, Michael R.H. Rockwood, Arnold B. Mitnitski, Kenneth Rockwood

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95 Citas (Scopus)

Resumen

We set out to describe the relationship between impaired balance, mobility and frailty, and relate these to risk of death. We examined a subsample of 1295 community-dwelling non-demented adults from the second wave of the Canadian Study of Health and Aging (CSHA), a prospective population-based cohort study. Frailty index (FI) scores were constructed from a standardized comprehensive geriatric assessment (FI-CGA). History of mobility impairments and falls were assessed. Timed-up-and-go (TUG) and functional reach (FR) performance were measured. The CSHA clinical frailty scale (CFS) was judged by a physician. Adverse outcomes were determined at CSHA-3, conducted 5 years later. The FI-CGA varied in association with impaired mobility and balance. A history of mobility problems was demonstrable at FI-CGA scores >0.12. This level of frailty also represented the most marked deterioration in performance measures (TUG and FR). FI-CGA scores best predicted mortality (HR 1.04 ± 0.02), proving to be a dominating factor in multivariate regression models that included mobility and balance markers. Only at the upper range of FI-CGA reported (>0.45) did all participants demonstrate mobility impairment. Impaired balance and mobility contribute to frailty, but neither is sufficient to define a participant as frail.

Idioma original	English
Páginas (desde-hasta)	79-83
Número de páginas	5
Publicación	Archives of Gerontology and Geriatrics
Volumen	53
N.º	1
DOI	https://doi.org/10.1016/j.archger.2010.06.013
Estado	Published - jul. 2011

Nota bibliográfica

Funding Information:
The authors thank other members of the Geriatric Medicine Research Unit who helped with the preparation of the data set. In particular, the assistance of Dr Nader Nallah, Samuel Searle and Tracey Fisher was invaluable. The study was supported by a grant from the Foundation Innovation Fund of the QEII Health Science Foundation , with additional funds from a Canadian Institutes of Health Research operating grant to the third and fourth authors. The first author was supported by a British Geriatrics Society Travel Grant, a Myre Sim Fund award from the Royal College of Physicians of Edinburgh, an Apgar Prize from Magdalen College Oxford, and a Wingate Foundation Medical Research Travel Grant. The fourth author is supported by the Dalhousie Medical Research Foundation as the Kathryn Allen Weldon Professor of Alzheimer Research.

ASJC Scopus Subject Areas

Health(social science)
Ageing
Gerontology
Geriatrics and Gerontology

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title = "Impairments in mobility and balance in relation to frailty",

abstract = "We set out to describe the relationship between impaired balance, mobility and frailty, and relate these to risk of death. We examined a subsample of 1295 community-dwelling non-demented adults from the second wave of the Canadian Study of Health and Aging (CSHA), a prospective population-based cohort study. Frailty index (FI) scores were constructed from a standardized comprehensive geriatric assessment (FI-CGA). History of mobility impairments and falls were assessed. Timed-up-and-go (TUG) and functional reach (FR) performance were measured. The CSHA clinical frailty scale (CFS) was judged by a physician. Adverse outcomes were determined at CSHA-3, conducted 5 years later. The FI-CGA varied in association with impaired mobility and balance. A history of mobility problems was demonstrable at FI-CGA scores >0.12. This level of frailty also represented the most marked deterioration in performance measures (TUG and FR). FI-CGA scores best predicted mortality (HR 1.04 ± 0.02), proving to be a dominating factor in multivariate regression models that included mobility and balance markers. Only at the upper range of FI-CGA reported (>0.45) did all participants demonstrate mobility impairment. Impaired balance and mobility contribute to frailty, but neither is sufficient to define a participant as frail.",

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Impairments in mobility and balance in relation to frailty

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

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