Interim estimates of 2014/15 influenza vaccine effectiveness in preventing laboratory-confirmed influenza-related hospitalisation from the serious outcomes surveillance network of the Canadian immunization research network, January 2015

S. A. McNeil, M. K. Andrew, L. Ye, F. Haguinet, T. F. Hatchette, M. Elsherif, J. Leblanc, A. Ambrose, A. McGeer, J. E. McElhaney, M. Loeb, D. Mackinnon-Cameron, R. Sharma, G. Dos Santos, V. Shinde

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48 Citas (Scopus)

Resumen

The 2014/15 influenza season in Canada has been characterised to date by early and intense activity dominated by influenza A(H3N2). A total of 99.0% (593/599) hospitalisations for laboratory-confirmed influenza with a known influenza virus type enrolled in sentinel hospitals of the Serious Outcomes Surveillance Network of the Canadian Immunization Research Network were due to influenza A. Of the 216 with a known subtype, influenza A(H3N2) accounted for 99.1% (n=214). Interim unmatched vaccine effectiveness (VE) estimates adjusted for age and presence of one or more medical comorbidities were determined by test-negative case-control design to be -16.8% (90% confidence interval (CI): -48.9 to 8.3) overall and -22.0% (90% CI: -66.5 to 10.7) for laboratory-confirmed influenza A(H3N2). Among adults aged under 65 years, the overall VE was 10.8% (90% CI: -50.2 to 47.0) while in adults aged 65 years or older, the overall VE was -25.4% (90% CI: -65.0 to 4.6).

Idioma originalEnglish
Páginas (desde-hasta)1-7
Número de páginas7
PublicaciónEurosurveillance
Volumen20
N.º5
DOI
EstadoPublished - 2015

ASJC Scopus Subject Areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Virology

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