KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication

Agriculture & Biology

• Human gammaherpesvirus 8 100%
• unfolded protein response 77%
• endoplasmic reticulum stress 27%
• virion 20%
• endoplasmic reticulum 19%
• virus replication 16%
• cells 13%
• transcription factors 11%
• proteins 9%
• transmembrane proteins 8%
• Herpesviridae 8%
• viral proteins 8%
• protein metabolism 7%
• post-translational modification 7%
• genes 7%
• protein synthesis 5%
• cell lines 5%
• transcription (genetics) 5%
• promoter regions 5%
• viruses 4%
• gene expression 4%
• synthesis 3%
• infection 3%
• dosage 3%

Medicine & Life Sciences

• Human Herpesvirus 8 73%
• Unfolded Protein Response 71%
• Endoplasmic Reticulum Stress 23%
• Endoplasmic Reticulum 20%
• Virion 20%
• Ectopic Gene Expression 15%
• Proteins 13%
• Activating Transcription Factor 6 11%
• Switch Genes 10%
• Protein Splicing 10%
• Herpesviridae 8%
• Messenger RNA 8%
• Viral Proteins 7%
• Post Translational Protein Processing 7%
• Virus Replication 7%
• Antiviral Agents 6%
• Genes 5%
• Transcription Factors 5%
• Viruses 4%
• Gene Expression 4%
• Cell Line 4%
• Infections 3%