Resumen
Purpose: To identify patient factors associated with improved pain scores, functional hip scores, health-related quality of life, and re-operation rates after arthroscopic management of femoroacetabular impingement (FAI). Methods: Using the comprehensive dataset from the multinational Femoroacetabular Impingement Randomized Controlled Trial (FIRST), a total of 13 prognostic factors that were chosen a priori were identified that would be expected to predict post-surgical outcomes. The primary outcome was pain assessed using a Visual Analogue Scale (VAS) and secondary outcomes included hip function (Hip Outcome Score [HOS] and International Hip Outcome Tool [iHOT-12]), health-related quality of life (Short Form-12 [SF-12] and Euro-Qol 5 Dimensions [EQ-5D]), and re-operation rate. A multivariable linear regression was used to analyse the change questionnaire scores from baseline to 12 months post-surgery including all 13 prognostic factors as independent variables. A total of 27 re-operation events were analysed at 24 months using a multivariable logistic regression including only the treatment group variable. Results: Of the 154 patients that had VAS scores completed at 12 months, a lower BMI (adjusted mean difference [aMD], 4.48 for a 5-unit decrease in BMI; 95% confidence interval [CI] 0.33–8.63; p = 0.035) was significantly associated with less pain. There was a significant negative association between increasing age and 1-year EQ-5D scores (aMD, − 0.04 for every 10-year increase in age; 95% CI − 0.07 to − 0.006; p = 0.020). The degree of impingement, severity of osteoarthritis, type of procedure, and adjudicated quality of surgery were not significantly associated with improvement across all outcomes at 12 months. Furthermore, there was no significant association between the treatment variable and the incidence of re-operation at 24 months. Conclusion: This study identified that lower BMI and age are predictive of improved pain and health utility scores, respectively, following arthroscopic management of FAI at 12 months post-surgery. These results may be a helpful adjunct in clinical decisions for this patient population when determining candidacy for surgical intervention. Level of evidence: I.
Idioma original | English |
---|---|
Páginas (desde-hasta) | 1461-1473 |
Número de páginas | 13 |
Publicación | Knee Surgery, Sports Traumatology, Arthroscopy |
Volumen | 29 |
N.º | 5 |
DOI | |
Estado | Published - may. 2021 |
Nota bibliográfica
Funding Information:Research grants were received from the Canadian Institutes of Health Research (principal investigators: ORA, MB), American Orthopaedic Society for Sports Medicine (principal investigator: ORA), Canadian Orthopaedic Foundation (principal investigators: ORA, MB), McMaster Surgical Associates (principal investigators: ORA, MB), and Hamilton Health Sciences Department of Surgery (principal investigator: ORA) for the FIRST trial. MB was funded, in part, by the Canada Research Chair in Musculoskeletal Trauma (McMaster University), which is unrelated to the present study.
Funding Information:
The Collaborating Group is known as the FIRST investigators. This is constituted of the following authors: steering committee: Olufemi R. Ayeni (Chair, McMaster University), Mohit Bhandari (Co-Chair, McMaster University), Asheesh Bedi (University of Michigan), Teppo J?rvinen (University of Helsinki), Volker Musahl (University of Pittsburgh), Douglas Naudie (University of Western Ontario), Matti Sepp?nen MD (Turku University), Gerard Slobogean (University of Maryland, Baltimore), Lehana Thabane (McMaster University). Methods Centre: Olufemi R. Ayeni (principal investigator); Nicole Simunovic (research manager); Andrew Duong, Matthew Skelly, Ajay Shanmugaraj, Sarah Crouch (project management); Sheila Sprague (research methodologist); Diane Heels-Ansdell, (statistical analysis); Lisa Buckingham (data management) (McMaster University). Data and safety monitoring committee: Tim Ramsay (Chair, Ottawa Hospital Research Institute), John Lee (University of Toronto), Petteri Kousa (Sports Clinic Hospital Dextra). Adjudication committee: Sasha Carsen (Chair, University of Ottawa), Hema Choudur (Hamilton Health Sciences), Yan Sim (McMaster University), Kelly Johnston (University of Calgary). Participating clinical sites?Canada: McMaster University Medical Centre (Hamilton, ON)?Olufemi R. Ayeni MD, PhD, FRCSC; Sarah Crouch BSc (Pharm); Andrew Duong MSc; Ajay Shanmugaraj BSc; Nicole Simunovic MSc; Matthew Skelly BSc; Sheila Sprague PhD. Dalhousie University (Halifax, NS)?Ivan Wong MD, FRCSC, Dip. Sports Medicine, MACM; Ryland Murphy BSc; Sara Sparavalo MASc. St. Michael?s Hospital (Toronto, ON)?Daniel Whelan MD, MSc, FRCSC; Ryan Khan BA, CCRP. Kingston Health Sciences Centre (Kingston, ON)?Gavin CA Wood MBChB, FRCS; Fiona Howells BPharm; Heather Grant MSc. London Health Sciences Centre (London, ON)?Douglas Naudie MD, MSc, FRCSC; Bryn Zomar MSc; Michael Pollock MSc. Fowler Kennedy Sport Medicine Clinic (London, ON)?Kevin Willits MD, FRCSC; Andrew Firth MSc; Stacey Wanlin; Alliya Remtulla MSc; Nicole Kaniki PhD. CHU de Qu?bec-Universit? Laval (Quebec City, QC)?Etienne L. Belzile MD; Sylvie Turmel RN. Participating Clinical Sites?International: Odense University Hospital (Odense, Denmark)?Uffe J?rgensen MD, Dr. Med Sci; Annie Gam-Pedersen RN. Tays Hatanp?? (Tampere University Hospital, Tampere, Finland)?Raine Sihvonen MD, PhD; Marko Raivio MD; Pirjo Toivonen PT. Turku University Hospital (Turku, Finland)?Matti Sepp?nen MD; Mari Pirjetta Routapohja RN. Post-trial statement: the Methods Centre at McMaster University coordinated the trial. The Methods Centre was responsible for programming trial randomisation, the maintenance of the database, data validation, data analyses, and study-centre coordination. The steering committee designed the trial, some members assisted with developing the statistical analysis plan, and vouch for the completeness and accuracy of the data and analyses.
Publisher Copyright:
© 2021, European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).
ASJC Scopus Subject Areas
- Surgery
- Orthopedics and Sports Medicine
PubMed: MeSH publication types
- Journal Article
- Multicenter Study
- Randomized Controlled Trial