Lymphomas and oncolytic virus therapy

Tommy Alain; Chandini Thirukkumaran; Donald G. Morris; Stefan J. Urbanski; Anna Janowska-Wieczorek; Patrick W.K. Lee; Anna E. Kossakowska

doi:10.3816/CLM.2003.n.019

Lymphomas and oncolytic virus therapy

Tommy Alain, Chandini Thirukkumaran, Donald G. Morris, Stefan J. Urbanski, Anna Janowska-Wieczorek, Patrick W.K. Lee, Anna E. Kossakowska

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Resumen

There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with oncolytic viruses took place > 80 years ago; however, it achieved little success. With modern technologies and current knowledge of viruses and cancer, there is an expectation for the discovery of efficient oncolytic viral therapies. This article will review the current knowledge of oncolytic viruses in relation to the treatment of lymphoma.

Idioma original	English
Páginas (desde-hasta)	104-111
Número de páginas	8
Publicación	Clinical Lymphoma
Volumen	4
N.º	2
DOI	https://doi.org/10.3816/CLM.2003.n.019
Estado	Published - sep. 2003
Publicado de forma externa	Sí

Nota bibliográfica

Funding Information:
This study was supported by grants to A.E.K. from the Alberta Cancer Board (#R1-170) and Leukemia Research Fund of Canada (The United Food and Commercial Workers Union Award).

ASJC Scopus Subject Areas

Cancer Research

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abstract = "There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with oncolytic viruses took place > 80 years ago; however, it achieved little success. With modern technologies and current knowledge of viruses and cancer, there is an expectation for the discovery of efficient oncolytic viral therapies. This article will review the current knowledge of oncolytic viruses in relation to the treatment of lymphoma.",

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AU - Thirukkumaran, Chandini

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AU - Janowska-Wieczorek, Anna

AU - Lee, Patrick W.K.

AU - Kossakowska, Anna E.

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Lymphomas and oncolytic virus therapy

Resumen

Nota bibliográfica

ASJC Scopus Subject Areas

ODS de las Naciones Unidas

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