MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein

Medicine & Life Sciences

• Niemann-Pick C1 Protein 100%
• Endosomes 64%
• Mitochondria 47%
• Cholesterol 42%
• Lymph Nodes 40%
• Type C Niemann-Pick Disease 23%
• Proteins 21%
• Mitochondrial Membranes 12%
• Cholesterol Side-Chain Cleavage Enzyme 5%
• Pregnenolone 5%
• Cricetulus 4%
• RNA Interference 3%
• Lipoproteins 3%
• Ovary 3%
• Neurodegenerative Diseases 3%
• Homeostasis 2%
• Mutation 2%

Chemical Compounds

• Cholesterol 51%
• Protein 23%
• Pregnenolone 5%
• Lipoprotein 4%
• Disorder 3%
• Mutation 3%
• Reduction 1%