TY - JOUR
T1 - Myocyte and myogenic stem cell transplantation in the heart
AU - Dowell, Joshua D.
AU - Rubart, Michael
AU - Pasumarthi, Kishore B.S.
AU - Soonpaa, Mark H.
AU - Field, Loren J.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Cellular transplantation is emerging as a potential mechanism with which to augment myocyte number in diseased hearts. To date a number of cell types have been shown to successfully engraft into the myocardium, including fetal, neonatal, and embryonic stem cell-derived cardiomyocytes, skeletal myoblasts, and stem cells with apparent cardiomyogenic potential. Here we provide a review of studies wherein myocytes or stem cells with myogenic potential have been transplanted into the heart. In addition, issues pertaining to the tracking and functional consequences of cell transplantation are discussed.
AB - Cellular transplantation is emerging as a potential mechanism with which to augment myocyte number in diseased hearts. To date a number of cell types have been shown to successfully engraft into the myocardium, including fetal, neonatal, and embryonic stem cell-derived cardiomyocytes, skeletal myoblasts, and stem cells with apparent cardiomyogenic potential. Here we provide a review of studies wherein myocytes or stem cells with myogenic potential have been transplanted into the heart. In addition, issues pertaining to the tracking and functional consequences of cell transplantation are discussed.
UR - http://www.scopus.com/inward/record.url?scp=0038369113&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038369113&partnerID=8YFLogxK
U2 - 10.1016/S0008-6363(03)00254-2
DO - 10.1016/S0008-6363(03)00254-2
M3 - Review article
C2 - 12757868
AN - SCOPUS:0038369113
SN - 0008-6363
VL - 58
SP - 336
EP - 350
JO - Cardiovascular Research
JF - Cardiovascular Research
IS - 2
ER -