Olfactory function in monozygotic twins discordant for schizophrenia

Lui C. Kopala, Kimberley P. Good, E. Fuller Torrey, William G. Honer

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

48 Citas (Scopus)

Resumen

Objective: Abnormalities of olfactory identification ability have been proposed as a marker of cerebral dysfunction in schizophrenia. The authors studied the potential role of genetic factors in olfactory dysfunction by assessing monozygotic twins discordant for schizophrenia and matched comparison subjects. Method: The subjects were 12 pairs of monozygotic twins discordant for schizophrenia and 12 healthy subjects matched for sex and age. Each subject completed the University of Pennsylvania Smell Identification Test. Results: The combined twin group scored significantly lower on smell identification than did the comparison group. The affected and unaffected twin groups did not differ from each other. Conclusions: Genetic factors may contribute to cerebral dysfunction as assessed by olfactory identification ability.

Idioma originalEnglish
Páginas (desde-hasta)134-136
Número de páginas3
PublicaciónAmerican Journal of Psychiatry
Volumen155
N.º1
DOI
EstadoPublished - 1998

ASJC Scopus Subject Areas

  • Psychiatry and Mental health

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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