Prevention of post-operative adhesions by N,O carboxymethyl chitosan

R. Kennedy, A. C. McAlister, C. Ciona, T. D.G. Lee

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Resumen

N,O carboxymethyl chitosan (NOCC), a biocompatible and non-inflammatory sulfated glycosaminoglycan structurally similar to heparin, hyaluronic acid, and carboxymethyl cellulose, was tested in three different rat models to assess its effect on post-operative adhesion formation, while at the same time ascertaining whether it would interfere with normal wound healing. It was found that NOCC reduces the incidence and intensity of surgical adhesions in rats without impairing wound healing.

Idioma originalEnglish
Páginas931
Número de páginas1
EstadoPublished - 1996
EventoProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duración: may. 29 1996jun. 2 1996

Conference

ConferenceProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CiudadToronto, Can
Período5/29/966/2/96

ASJC Scopus Subject Areas

  • General Materials Science

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