SARS-CoV-2 infection in technology-dependent children: a multicenter case series

Joan Robinson, Tammie Dewan, Shaun K. Morris, Ari Bitnun, Peter Gill, Tala El Tal, Ronald M. Laxer, E. Ann Yeh, Carmen Yea, Rolando Ulloa-Gutierrez, Helena Brenes-Chacon, Adriana Yock-Corrales, Gabriela Ivankovich-Escoto, Alejandra Soriano-Fallas, Marcela Hernandez de Mezerville, Jesse Papenburg, Marie Astrid Lefebvre, Alireza Nateghian, Behzad Haghighi Aski, Ali ManafiRachel Dwilow, Jared Bullard, Suzette Cooke, Lea Restivo, Alison Lopez, Manish Sadarangani, Ashley Roberts, Nicole Le Saux, Jennifer Bowes, Rupeena Purewal, Janell Lautermilch, Jacqueline K. Wong, Dominique Piche, Karina A. Top, Cheryl Foo, Luc Panetta, Joanna Merckx, Michelle Barton

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Purpose: The objective of this study was to describe the clinical course and outcomes in children with technology dependence (TD) hospitalized with SARS-CoV-2 infection. Methods: Seventeen pediatric hospitals (15 Canadian and one each in Iran and Costa Rica) included children up to 17 years of age admitted February 1, 2020, through May 31, 2021, with detection of SARS-CoV-2. For those with TD, data were collected on demographics, clinical course and outcome. Results: Of 691 children entered in the database, 42 (6%) had TD of which 22 had feeding tube dependence only, 9 were on supplemental oxygen only, 3 had feeding tube dependence and were on supplemental oxygen, 2 had a tracheostomy but were not ventilated, 4 were on non-invasive ventilation, and 2 were on mechanical ventilation prior to admission. Three of 42 had incidental SARS-CoV-2 infection. Two with end-stage underlying conditions were transitioned to comfort care and died. Sixteen (43%) of the remaining 37 cases required increased respiratory support from baseline due to COVID-19 while 21 (57%) did not. All survivors were discharged home. Conclusion: Children with TD appear to have an increased risk of COVID-19 hospitalization. However, in the absence of end-stage chronic conditions, all survived to discharge.

Idioma originalEnglish
PublicaciónInfection
DOI
EstadoAccepted/In press - 2022

Nota bibliográfica

Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

ASJC Scopus Subject Areas

  • Microbiology (medical)
  • Infectious Diseases

PubMed: MeSH publication types

  • Journal Article

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