TY - JOUR
T1 - SARS-CoV-2 infection in technology-dependent children
T2 - a multicenter case series
AU - Robinson, Joan
AU - Dewan, Tammie
AU - Morris, Shaun K.
AU - Bitnun, Ari
AU - Gill, Peter
AU - Tal, Tala El
AU - Laxer, Ronald M.
AU - Yeh, E. Ann
AU - Yea, Carmen
AU - Ulloa-Gutierrez, Rolando
AU - Brenes-Chacon, Helena
AU - Yock-Corrales, Adriana
AU - Ivankovich-Escoto, Gabriela
AU - Soriano-Fallas, Alejandra
AU - Mezerville, Marcela Hernandez de
AU - Papenburg, Jesse
AU - Lefebvre, Marie Astrid
AU - Nateghian, Alireza
AU - Aski, Behzad Haghighi
AU - Manafi, Ali
AU - Dwilow, Rachel
AU - Bullard, Jared
AU - Cooke, Suzette
AU - Restivo, Lea
AU - Lopez, Alison
AU - Sadarangani, Manish
AU - Roberts, Ashley
AU - Le Saux, Nicole
AU - Bowes, Jennifer
AU - Purewal, Rupeena
AU - Lautermilch, Janell
AU - Wong, Jacqueline K.
AU - Piche, Dominique
AU - Top, Karina A.
AU - Foo, Cheryl
AU - Panetta, Luc
AU - Merckx, Joanna
AU - Barton, Michelle
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.
PY - 2022
Y1 - 2022
N2 - Purpose: The objective of this study was to describe the clinical course and outcomes in children with technology dependence (TD) hospitalized with SARS-CoV-2 infection. Methods: Seventeen pediatric hospitals (15 Canadian and one each in Iran and Costa Rica) included children up to 17 years of age admitted February 1, 2020, through May 31, 2021, with detection of SARS-CoV-2. For those with TD, data were collected on demographics, clinical course and outcome. Results: Of 691 children entered in the database, 42 (6%) had TD of which 22 had feeding tube dependence only, 9 were on supplemental oxygen only, 3 had feeding tube dependence and were on supplemental oxygen, 2 had a tracheostomy but were not ventilated, 4 were on non-invasive ventilation, and 2 were on mechanical ventilation prior to admission. Three of 42 had incidental SARS-CoV-2 infection. Two with end-stage underlying conditions were transitioned to comfort care and died. Sixteen (43%) of the remaining 37 cases required increased respiratory support from baseline due to COVID-19 while 21 (57%) did not. All survivors were discharged home. Conclusion: Children with TD appear to have an increased risk of COVID-19 hospitalization. However, in the absence of end-stage chronic conditions, all survived to discharge.
AB - Purpose: The objective of this study was to describe the clinical course and outcomes in children with technology dependence (TD) hospitalized with SARS-CoV-2 infection. Methods: Seventeen pediatric hospitals (15 Canadian and one each in Iran and Costa Rica) included children up to 17 years of age admitted February 1, 2020, through May 31, 2021, with detection of SARS-CoV-2. For those with TD, data were collected on demographics, clinical course and outcome. Results: Of 691 children entered in the database, 42 (6%) had TD of which 22 had feeding tube dependence only, 9 were on supplemental oxygen only, 3 had feeding tube dependence and were on supplemental oxygen, 2 had a tracheostomy but were not ventilated, 4 were on non-invasive ventilation, and 2 were on mechanical ventilation prior to admission. Three of 42 had incidental SARS-CoV-2 infection. Two with end-stage underlying conditions were transitioned to comfort care and died. Sixteen (43%) of the remaining 37 cases required increased respiratory support from baseline due to COVID-19 while 21 (57%) did not. All survivors were discharged home. Conclusion: Children with TD appear to have an increased risk of COVID-19 hospitalization. However, in the absence of end-stage chronic conditions, all survived to discharge.
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U2 - 10.1007/s15010-022-01910-y
DO - 10.1007/s15010-022-01910-y
M3 - Article
C2 - 36038707
AN - SCOPUS:85141348699
SN - 0300-8126
JO - Infection
JF - Infection
ER -
