“Sucrose Analgesia” and Diphtheria-Tetanus-Pertussis Immunizations at 2 and 4 Months

Ronald G. Barr, Simon N. Young, Janice H. Wright, Keri Leigh Cassidy, Lisa Hendricks, Yolande Bedard, John Yaremko, Denis Leduc, Steven Treherne

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

85 Citas (Scopus)

Resumen

In human newborns, small amounts of sucrose reduce crying with procedural pain by about 50%. To determine whether “sucrose analgesia” could be extended to painful procedures beyond the newborn period, 57 infants were randomly assigned to receive three 250-$mUl doses of 50% sucrose solution (g/100 mL) or water before their diphtheria-tetanus-pertussis immunizations at 2 and 4 months of age. Crying during and after injection was measured separately to determine whether sucrose modified crying during the noxious stimulus, recovery from the stimulus, or both. Sucrose was effective in reducing crying only from 83 to 69%, and the reduction was limited to the postinjection period. We conclude that, although sucrose continues to have some effect beyond the newborn period, the effect is limited to recovery from the noxious stimulus, is clinically modest, and is probably smaller than in the newborn period.

Idioma originalEnglish
Páginas (desde-hasta)220-225
Número de páginas6
PublicaciónJournal of Developmental and Behavioral Pediatrics
Volumen16
N.º4
DOI
EstadoPublished - ago. 1995
Publicado de forma externa

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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