The addition of intravenous propofol and ketorolac to a sevoflurane anesthetic lessens emergence agitation in children having bilateral myringotomy with tympanostomy tube insertion: A prospective observational study

Brandon D’eon, Thomas Hackmann, A. Stuart Wright

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

5 Citas (Scopus)

Resumen

The aim of this prospective observational study was to determine if children undergoing bilateral myringotomy and tympanostomy tube insertion with a sevoflurane anesthetic plus intravenous propofol and ketorolac experienced a lower incidence of emergence agitation than those receiving a sevoflurane anesthetic alone. Duration of procedure, length of stay in post-anaesthesia care and level of nursing effort required to care for patients were also assessed. In this study, 49 children younger than 13 years of age received a sevoflurane anesthetic. Fifty-one percent of these patients also received a single injection of propofol 1 mg/kg and ketorolac 0.5 mg/kg at the end of the procedure. Patients were assessed for emergence agitation using the Pediatric Anesthesia Emergence Delirium scale in the post-anaesthesia care unit. Four children receiving a sevoflurane anesthetic alone experienced emergence agitation, while no children receiving propofol and ketorolac experienced emergence agitation (p = 0.05). The length of stay until discharge from the hospital was 6.98 min longer for patients receiving propofol and ketorolac but did not reach statistical significance (p = 0.23). Nurses reported greater ease in caring for patients receiving the propofol and ketorolac injection (recovery questionnaire score 4.50 vs. 3.75, p = 0.002). In this study, adding a single injection of intravenous propofol and ketorolac to the end of a brief sevoflurane anesthetic for bilateral myringotomy with tube insertion was associated with a lower incidence of emergence agitation without significantly increasing the time to discharge from the hospital.

Idioma originalEnglish
Número de artículo96
PublicaciónChildren
Volumen7
N.º8
DOI
EstadoPublished - ago. 2020

Nota bibliográfica

Funding Information:
Acknowledgments: The authors would like to thank S. Amey, for assisting in obtaining research ethics approval, S.P. Mackinnon for assisting with our statistical analysis, as well as the PACU staff and nurses for their support and dedication to improving patient care. This study was supported by a Director’s Fund Summer Research Studentship from the Dalhousie Medical Research Fund.

Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health

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