TY - JOUR
T1 - THE PERMEABILITY OF PINCHED‐OFF NERVE ENDINGS TO SODIUM, POTASSIUM AND CHLORIDE AND THE EFFECTS OF GRAMICIDIN
AU - Keen, P.
AU - White, T. D.
PY - 1971/6
Y1 - 1971/6
N2 - Abstract— The passive permeability of synaptosomes to ions was measured by a light‐scattering technique. Synaptosomes were freely permeable to acetate, HCO3_, SCN−and NH4+ and were impermeable to choline and SO42‐. Gramicidin D selectively increased the permeability of synaptosomes to Na+ and K+ ions. The relative permeabilities of Na+, K+ and Cl−, measured in the presence of a number of more permeant counter‐ions, was in the ratio 1:19:12. These values are discussed in terms of the source of the resting potential.
AB - Abstract— The passive permeability of synaptosomes to ions was measured by a light‐scattering technique. Synaptosomes were freely permeable to acetate, HCO3_, SCN−and NH4+ and were impermeable to choline and SO42‐. Gramicidin D selectively increased the permeability of synaptosomes to Na+ and K+ ions. The relative permeabilities of Na+, K+ and Cl−, measured in the presence of a number of more permeant counter‐ions, was in the ratio 1:19:12. These values are discussed in terms of the source of the resting potential.
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U2 - 10.1111/j.1471-4159.1971.tb12038.x
DO - 10.1111/j.1471-4159.1971.tb12038.x
M3 - Article
C2 - 5567898
AN - SCOPUS:0015073037
SN - 0022-3042
VL - 18
SP - 1097
EP - 1103
JO - Journal of Neurochemistry
JF - Journal of Neurochemistry
IS - 6
ER -