TY - JOUR
T1 - Application of the probabilistic approach to reporting breast fine needle aspiration in males
AU - MacIntosh, Rebecca F.
AU - Merrimen, Jennifer L.
AU - Barnes, Penny J.
PY - 2008
Y1 - 2008
N2 - Objective: To apply the probabilistic approach to a series of fine needle aspiration (FNA) samples of male breast lesions and determine the accuracy and reproducibility of this method of reporting in men. Study Design: All male breast surgical specimens with a preoperative breast FNA at our institution from 1994 to 2005 were identified. The FNAs were blindly reviewed by 2 groups of observers and classified in 1 of 5 categories using published reporting guidelines: positive, suspicious, atypical, proliferative without atypia and unremarkable. The histologic and cytologic diagnoses were correlated. The interobserver variation was determined. Results: A total of 138 FNAs were performed for 123 male patients. Histologic correlation was available for 23 satisfactory FNAs. A total of 11 of 11 carcinomas (100%) were classified as positive, suspicious or atypical. Of 12 benign masses, 11 (91.6%) were classified as proliferative without atypia or unremarkable. One case of gynecomastia was classified as atypical by 1 observer but deemed not atypical with consen sus review. The κ statistic for benign and atypical/suspicious/malignant categories was 0.90. Conclusion: Based on this series, the probabilistic approach can be applied to the reporting of FNAs of male breast lesions. Gyneco mastia may result in an atypical cytologic diagnosis.
AB - Objective: To apply the probabilistic approach to a series of fine needle aspiration (FNA) samples of male breast lesions and determine the accuracy and reproducibility of this method of reporting in men. Study Design: All male breast surgical specimens with a preoperative breast FNA at our institution from 1994 to 2005 were identified. The FNAs were blindly reviewed by 2 groups of observers and classified in 1 of 5 categories using published reporting guidelines: positive, suspicious, atypical, proliferative without atypia and unremarkable. The histologic and cytologic diagnoses were correlated. The interobserver variation was determined. Results: A total of 138 FNAs were performed for 123 male patients. Histologic correlation was available for 23 satisfactory FNAs. A total of 11 of 11 carcinomas (100%) were classified as positive, suspicious or atypical. Of 12 benign masses, 11 (91.6%) were classified as proliferative without atypia or unremarkable. One case of gynecomastia was classified as atypical by 1 observer but deemed not atypical with consen sus review. The κ statistic for benign and atypical/suspicious/malignant categories was 0.90. Conclusion: Based on this series, the probabilistic approach can be applied to the reporting of FNAs of male breast lesions. Gyneco mastia may result in an atypical cytologic diagnosis.
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U2 - 10.1159/000325593
DO - 10.1159/000325593
M3 - Article
AN - SCOPUS:52249086256
SN - 0001-5547
VL - 52
SP - 530
EP - 534
JO - Acta Cytologica
JF - Acta Cytologica
IS - 5
ER -