Are there serotonergic projections from raphe and retrotrapezoid nuclei to the ventral respiratory group in the rat?

C. A. Connelly, H. H. Ellenberger, J. L. Feldman

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Résumé

The relationship of serotonergic neurons in raphe and ventrolateral medullary regions to neurons projecting to the rostral ventral respiratory group in the rat were investigated using combined immunohistochemical and retrograde labeling techniques. Serotonergic and non-serotonergic neurons retrogradely labeled with rhodamine beads were found intermingled in the larger population of serotonin-immunoreactive neurons in raphe pallidus, obscurus and magnus. In addition, a cell group analogous to the retrotrapezoid nucleus in the cat was identified in the rat ventrolateral medulla. Retrotrapezoid neurons, which exhibited exclusively ipsilateral projections to the ventral respiratory group, were located lateral to clusters of serotonergic cells near the ventral surface, but were not serotonin immunoreactive.

Langue d'origineEnglish
Pages (de-à)34-40
Nombre de pages7
JournalNeuroscience Letters
Volume105
Numéro de publication1-2
DOI
Statut de publicationPublished - oct. 23 1989
Publié à l'externeOui

Note bibliographique

Funding Information:
Special thanks to Ms. Marianne Otto for her technical assistance with these experiments. Supported by NIH Grant HL37941. C.A.C. is a Parker B. Francis Foundation Fellow.

ASJC Scopus Subject Areas

  • General Neuroscience

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