Résumé
The purpose of this study was to determine if the medullary neurons that provide the primary excitatiry drive to phrenic motoneurons (i.e., rostral ventral respiratory group, rVRG) are a source of double synapse formation in the phrenic nucleus after spinal cord hemisection. The axons of rVRG neurons either ipsilateral or contralateral to the hemisection were labeled by injection of a mixture of HRP and WGA-HRP into the rostral ventral respiratory group. Phrenic motoneurons ipsilateral and caudal to the hemisection were labeled by the retrograde transport of HRP. The ultrastructural results indicated that after hemisection, rVRG neurons from both sides of the medulla formed labelled double synapses in the phrenic nucleus.
| Langue d'origine | English |
|---|---|
| Pages (de-à) | 169-173 |
| Nombre de pages | 5 |
| Journal | Brain Research |
| Volume | 600 |
| Numéro de publication | 1 |
| DOI | |
| Statut de publication | Published - janv. 8 1993 |
| Publié à l'externe | Oui |
Note bibliographique
Funding Information:This work was supported by NIH Grants NS14705 (H.G.G.) and NS 24742 (J.L.F.).
ASJC Scopus Subject Areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology
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Goshgarian, H. G., Ellenberger, H. H., & Feldman, J. L. (1993). Bulbospinal respiratory neurons are a source of double synapses onto phrenic motoneurons following cervical spinal cord hemisection in adult rats. Brain Research, 600(1), 169-173. https://doi.org/10.1016/0006-8993(93)90417-L