Canadian Pediatric Surgical Network: a population-based pediatric surgery network and database for analyzing surgical birth defects. The first 100 cases of gastroschisis

Erik D. Skarsgard, Jennifer Claydon, Sarah Bouchard, Peter C.W. Kim, Shoo K. Lee, Jean Martin Laberge, Douglas McMillan, Peter von Dadelszen, Natalie Yanchar

Résultat de recherche: Articleexamen par les pairs

88 Citations (Scopus)

Résumé

Purpose: Outcomes studies for gastroschisis are constrained by small numbers, prolonged accrual, and nonstandardized data collection. The aim of this study is to create a national pediatric surgical network and database for gastroschisis (GS) that tracks cases from diagnosis to hospital discharge. Methods: The 16-center network serves a population of 32 million. Gastroschisis cases are ascertained at prenatal diagnosis. Perinatal data include maternal risk and fetal ultrasound variables, delivery plan and outcome, a postnatal bowel injury score, intended and actual surgical treatment, and neonatal outcomes. Institutional review board-approved data collection conforms to regional privacy legislation. Deidentified data are centralized and accessible for research through the network steering committee. Results: To date, 114 cases of pre- and/or postnatal gastroschisis have been uploaded. Of 106 live-born infants (40 [38%] by cesarean delivery), 100 had complete records, and overall survival to discharge was 96%, with a mean survivor length of stay (LOS) of 46 days. Infants treated with attempted urgent closure (61%) had significantly shorter LOS (42 vs 57days; P = .048) but comparable LOS compared with those treated with silos and delayed closure. Fetal bowel dilation 18 mm or greater did not predict a difference in outcome. Conclusion: Population-based databases allow rapid case accrual and enable studies that should aid in the identification of optimal perinatal treatment.

Langue d'origineEnglish
Pages (de-à)30-34
Nombre de pages5
JournalJournal of Pediatric Surgery
Volume43
Numéro de publication1
DOI
Statut de publicationPublished - janv. 2008

ASJC Scopus Subject Areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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