Cellular immune defenses of Drosophila melanogaster

Brendon Parsons; Edan Foley

doi:10.1016/j.dci.2015.12.019

Cellular immune defenses of Drosophila melanogaster

Brendon Parsons, Edan Foley

Résultat de recherche: Article › examen par les pairs

53 Citations (Scopus)

Résumé

Drosophila melanogaster is a widely used model for the characterization of blood cell development and function, with an array of protocols for the manipulation and visualization of fixed or live cells in vitro or in vivo. Researchers have deployed these techniques to reveal Drosophila hemocytes as a remarkably versatile cell type that engulfs apoptotic corpses; neutralizes invading parasites; seals epithelial wounds; and deposits extracellular matrix proteins. In this review, we will discuss the key features of Drosophila hemocyte development and function, and identify similarities with vertebrate counterparts.

Langue d'origine	English
Pages (de-à)	95-101
Nombre de pages	7
Journal	Developmental and Comparative Immunology
Volume	58
DOI	https://doi.org/10.1016/j.dci.2015.12.019
Statut de publication	Published - mai 1 2016
Publié à l'externe	Oui

Note bibliographique

Funding Information:
The research performed in the lab of EF is supported by a grant from the Canadian Institutes of Health Research ( MOP 77746 ).

Publisher Copyright:
© 2016 Elsevier Ltd.

ASJC Scopus Subject Areas

Immunology
Developmental Biology

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10.1016/j.dci.2015.12.019

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Cellular immune defenses of Drosophila melanogaster

Résumé

Note bibliographique

ASJC Scopus Subject Areas

Accès au document

Autres fichiers et liens

Empreinte numérique

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