Complete NMR assignments of the antibacterial biflavonoid GB1 from Garcinia kola

Quan Bin Han; Song Fong Lee; Chun Feng Qiao; Zhen Dan He; Jing Zheng Song; Han Dong Sun; Hong Xi Xu

doi:10.1248/cpb.53.1034

Complete NMR assignments of the antibacterial biflavonoid GB1 from Garcinia kola

Quan Bin Han, Song Fong Lee, Chun Feng Qiao, Zhen Dan He, Jing Zheng Song, Han Dong Sun, Hong Xi Xu

Medicine

Résultat de recherche: Article › examen par les pairs

46 Citations (Scopus)

Résumé

From the antibacterial fraction of the roots of Garcinia kola, 3″,4′,4‴,5,5″,7,7″-heptahydroxy-3, 8″-biflavanone (GB1) was isolated as the major constituent, whose interesting conformations were studied on the basis of its 1D and 2D NMR spectra obtained at different temperatures and in different solvents. GB1 showed antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) with MIC of 32 and 128 μg/ml, respectively.

Langue d'origine	English
Pages (de-à)	1034-1036
Nombre de pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	53
Numéro de publication	8
DOI	https://doi.org/10.1248/cpb.53.1034
Statut de publication	Published - août 2005

ASJC Scopus Subject Areas

General Chemistry
Drug Discovery

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

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10.1248/cpb.53.1034

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abstract = "From the antibacterial fraction of the roots of Garcinia kola, 3″,4′,4‴,5,5″,7,7″-heptahydroxy-3, 8″-biflavanone (GB1) was isolated as the major constituent, whose interesting conformations were studied on the basis of its 1D and 2D NMR spectra obtained at different temperatures and in different solvents. GB1 showed antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) with MIC of 32 and 128 μg/ml, respectively.",

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AU - Sun, Han Dong

AU - Xu, Hong Xi

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Complete NMR assignments of the antibacterial biflavonoid GB1 from Garcinia kola

Résumé

ASJC Scopus Subject Areas

PubMed: MeSH publication types

Accès au document

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