Confirmation of the influence of a Chromosome 7 locus on susceptibility to audiogenic seizures

Paul E. Neumann; Robert L. Collins

doi:10.1007/BF00292152

Confirmation of the influence of a Chromosome 7 locus on susceptibility to audiogenic seizures

Paul E. Neumann, Robert L. Collins

Résultat de recherche: Article › examen par les pairs

24 Citations (Scopus)

Résumé

Mouse strain differences in susceptibility to audiogenic seizures (AGS) are due to allelic differences at multiple genetic loci. Three loci that influence susceptibility to AGS have been mapped on Chromosomes (Chr) 12, 4, and 7 (Asp-1, Asp-2, and Asp-3, respectively). Here we report evidence that confirms linkage of Asp-3 to c on Chr 7 and parental effects on AGS susceptibility, but not genomic imprinting of Asp-3.

Langue d'origine	English
Pages (de-à)	250-253
Nombre de pages	4
Journal	Mammalian Genome
Volume	3
Numéro de publication	5
DOI	https://doi.org/10.1007/BF00292152
Statut de publication	Published - mai 1992
Publié à l'externe	Oui

ASJC Scopus Subject Areas

Genetics

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10.1007/BF00292152

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abstract = "Mouse strain differences in susceptibility to audiogenic seizures (AGS) are due to allelic differences at multiple genetic loci. Three loci that influence susceptibility to AGS have been mapped on Chromosomes (Chr) 12, 4, and 7 (Asp-1, Asp-2, and Asp-3, respectively). Here we report evidence that confirms linkage of Asp-3 to c on Chr 7 and parental effects on AGS susceptibility, but not genomic imprinting of Asp-3.",

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AB - Mouse strain differences in susceptibility to audiogenic seizures (AGS) are due to allelic differences at multiple genetic loci. Three loci that influence susceptibility to AGS have been mapped on Chromosomes (Chr) 12, 4, and 7 (Asp-1, Asp-2, and Asp-3, respectively). Here we report evidence that confirms linkage of Asp-3 to c on Chr 7 and parental effects on AGS susceptibility, but not genomic imprinting of Asp-3.

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Confirmation of the influence of a Chromosome 7 locus on susceptibility to audiogenic seizures

Résumé

ASJC Scopus Subject Areas

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Empreinte numérique

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