Résumé
A fatality following ingestion of the tricyclic antidepressant trimipramine (Surmontil)® is described. Quantitation was performed by high-performance liquid chromatography. Trimipramine and desmethyltrimipramlne concentrations were 4.8 and 2.1 mg/L, respectively, in postmortem blood. The concentration of trimipramine, desmethyltrimipramine, and their respective 2-hydroxy metabolites were also measured in liver and urine. Analysis of gastric contents revealed a tricyclic antidepressant drug. These findings are compared to previously published reports of trimipramine-related fatalities.
| Langue d'origine | English |
|---|---|
| Pages (de-à) | 154-163 |
| Nombre de pages | 10 |
| Journal | Journal of Analytical Toxicology |
| Volume | 11 |
| Numéro de publication | 4 |
| DOI | |
| Statut de publication | Published - juill. 1 1987 |
ASJC Scopus Subject Areas
- Analytical Chemistry
- Environmental Chemistry
- Toxicology
- Health, Toxicology and Mutagenesis
- Chemical Health and Safety
PubMed: MeSH publication types
- Case Reports
- Journal Article