Effect of sympathomimetic drugs on canine bladder Surgical model for assessment of regional differences

John W. Downie; Said A. Awad; Denis W. Lywood; Andrew W. Bruce

doi:10.1016/0090-4295(74)90101-0

Effect of sympathomimetic drugs on canine bladder Surgical model for assessment of regional differences

John W. Downie, Said A. Awad, Denis W. Lywood, Andrew W. Bruce

Résultat de recherche: Article › examen par les pairs

Résumé

A surgical procedure is described in which the canine bladder was divided into body and base. The two-chambered bladder thus formed was used to assess the effect of sympathomimetic drugs in situ. Stimulation of either alpha- or beta-receptors produced a change in pressure in both chambers. The bladder base showed a greater sensitivity to alpha-receptor stimulation than did the body of the bladder. No difference in sensitivity to beta-receptor stimulation was noted between body and base.

Langue d'origine	English
Pages (de-à)	18-25
Nombre de pages	8
Journal	Urology
Volume	4
Numéro de publication	1
DOI	https://doi.org/10.1016/0090-4295(74)90101-0
Statut de publication	Published - juill. 1974
Publié à l'externe	Oui

Note bibliographique

Funding Information:
by a grant from the Medical Research

ASJC Scopus Subject Areas

Urology

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

Accès au document

10.1016/0090-4295(74)90101-0

Autres fichiers et liens

Citer

@article{82f4480528914e8ebc47126890d45170,

title = "Effect of sympathomimetic drugs on canine bladder Surgical model for assessment of regional differences",

abstract = "A surgical procedure is described in which the canine bladder was divided into body and base. The two-chambered bladder thus formed was used to assess the effect of sympathomimetic drugs in situ. Stimulation of either alpha- or beta-receptors produced a change in pressure in both chambers. The bladder base showed a greater sensitivity to alpha-receptor stimulation than did the body of the bladder. No difference in sensitivity to beta-receptor stimulation was noted between body and base.",

author = "Downie, {John W.} and Awad, {Said A.} and Lywood, {Denis W.} and Bruce, {Andrew W.}",

note = "Funding Information: by a grant from the Medical Research",

year = "1974",

month = jul,

doi = "10.1016/0090-4295(74)90101-0",

language = "English",

volume = "4",

pages = "18--25",

journal = "Urology",

issn = "0090-4295",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Effect of sympathomimetic drugs on canine bladder Surgical model for assessment of regional differences

AU - Downie, John W.

AU - Awad, Said A.

AU - Lywood, Denis W.

AU - Bruce, Andrew W.

N1 - Funding Information: by a grant from the Medical Research

PY - 1974/7

Y1 - 1974/7

N2 - A surgical procedure is described in which the canine bladder was divided into body and base. The two-chambered bladder thus formed was used to assess the effect of sympathomimetic drugs in situ. Stimulation of either alpha- or beta-receptors produced a change in pressure in both chambers. The bladder base showed a greater sensitivity to alpha-receptor stimulation than did the body of the bladder. No difference in sensitivity to beta-receptor stimulation was noted between body and base.

AB - A surgical procedure is described in which the canine bladder was divided into body and base. The two-chambered bladder thus formed was used to assess the effect of sympathomimetic drugs in situ. Stimulation of either alpha- or beta-receptors produced a change in pressure in both chambers. The bladder base showed a greater sensitivity to alpha-receptor stimulation than did the body of the bladder. No difference in sensitivity to beta-receptor stimulation was noted between body and base.

UR - http://www.scopus.com/inward/record.url?scp=49549159172&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49549159172&partnerID=8YFLogxK

U2 - 10.1016/0090-4295(74)90101-0

DO - 10.1016/0090-4295(74)90101-0

M3 - Article

C2 - 21322977

AN - SCOPUS:49549159172

SN - 0090-4295

VL - 4

SP - 18

EP - 25

JO - Urology

JF - Urology

IS - 1

ER -

Effect of sympathomimetic drugs on canine bladder Surgical model for assessment of regional differences

Résumé

Note bibliographique

ASJC Scopus Subject Areas

PubMed: MeSH publication types

Accès au document

Autres fichiers et liens

Empreinte numérique

Citer