Effects of exercise dose and type on sleep quality in breast cancer patients receiving chemotherapy: A multicenter randomized trial

Kerry S. Courneya; Roanne J. Segal; John R. Mackey; Karen Gelmon; Christine M. Friedenreich; Yutaka Yasui; Robert D. Reid; Diana Jespersen; Diane Cook; Carolyn Proulx; Linda Trinh; Lianne B. Dolan; Evyanne Wooding; Cynthia C. Forbes; Donald C. McKenzie

doi:10.1007/s10549-014-2883-0

Effects of exercise dose and type on sleep quality in breast cancer patients receiving chemotherapy: A multicenter randomized trial

Kerry S. Courneya, Roanne J. Segal, John R. Mackey, Karen Gelmon, Christine M. Friedenreich, Yutaka Yasui, Robert D. Reid, Diana Jespersen, Diane Cook, Carolyn Proulx, Linda Trinh, Lianne B. Dolan, Evyanne Wooding, Cynthia C. Forbes, Donald C. McKenzie

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Résumé

To examine the effects of different doses and types of exercise on sleep quality in breast cancer patients receiving chemotherapy. A multicenter trial in Canada randomized 301 breast cancer patients between 2008 and 2011 to thrice weekly, supervised exercise during chemotherapy consisting of either a standard dose of 25-30 min of aerobic exercise (STAN; n = 96), a higher dose of 50-60 min of aerobic exercise (HIGH; n = 101), or a combined dose of 50-60 min of aerobic and resistance exercise (COMB; n = 104). The secondary sleep outcomes in the trial were assessed by the Pittsburgh Sleep Quality Index (PSQI) at baseline, twice during chemotherapy, and postchemotherapy. We analyzed the global PSQI and the component scores. Repeated measures analyses of variance indicated that the HIGH group was statistically superior to the STAN group for global sleep quality (mean group difference = -0.90; 95 % CI -0.05 to -1.76; p = 0.039) as well as subjective sleep quality (p = 0.028) and sleep latency (p = 0.049). The COMB group was borderline statistically superior to the STAN group for global sleep quality (mean group difference = -0.76; 95 % CI +0.11 to -1.62; p = 0.085) as well as sleep duration (p = 0.051); and statistically superior for sleep efficiency (p = 0.040), and percentage of poor sleepers (p = 0.045). Compared to a standard volume of aerobic exercise, higher volumes of both aerobic and combined exercise improved some aspects of sleep quality during breast cancer chemotherapy. Exercise may be an attractive option to manage sleep dysfunction in cancer patients during chemotherapy.

Langue d'origine	English
Pages (de-à)	361-369
Nombre de pages	9
Journal	Breast Cancer Research and Treatment
Volume	144
Numéro de publication	2
DOI	https://doi.org/10.1007/s10549-014-2883-0
Statut de publication	Published - avr. 2014
Publié à l'externe	Oui

Note bibliographique

Funding Information:
Acknowledgments This work was supported by a Grant from the Canadian Breast Cancer Research Alliance. KSC and YY are supported by the Canada Research Chairs Program. YY is also supported by the Alberta Innovates-Health Solutions. CMF is supported by a Health Senior Scholar Award from Alberta Innovates-Health Solutions and through the Alberta Cancer Foundation’s Weekend to End Women’s Cancers Breast Cancer Chair. LT was supported by a Health Studentship from Alberta Innovates-Health Solutions.

ASJC Scopus Subject Areas

Oncology
Cancer Research

ODD de l’ONU

Cette action contribue à la réalisation des objectifs de développement durable suivants

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10.1007/s10549-014-2883-0

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Courneya, K. S., Segal, R. J., Mackey, J. R., Gelmon, K., Friedenreich, C. M., Yasui, Y., Reid, R. D., Jespersen, D., Cook, D., Proulx, C., Trinh, L., Dolan, L. B., Wooding, E., Forbes, C. C., & McKenzie, D. C. (2014). Effects of exercise dose and type on sleep quality in breast cancer patients receiving chemotherapy: A multicenter randomized trial. Breast Cancer Research and Treatment, 144(2), 361-369. https://doi.org/10.1007/s10549-014-2883-0

Courneya, KS, Segal, RJ, Mackey, JR, Gelmon, K, Friedenreich, CM, Yasui, Y, Reid, RD, Jespersen, D, Cook, D, Proulx, C, Trinh, L, Dolan, LB, Wooding, E, Forbes, CC & McKenzie, DC 2014, 'Effects of exercise dose and type on sleep quality in breast cancer patients receiving chemotherapy: A multicenter randomized trial', Breast Cancer Research and Treatment, vol. 144, n° 2, pp. 361-369. https://doi.org/10.1007/s10549-014-2883-0

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title = "Effects of exercise dose and type on sleep quality in breast cancer patients receiving chemotherapy: A multicenter randomized trial",

abstract = "To examine the effects of different doses and types of exercise on sleep quality in breast cancer patients receiving chemotherapy. A multicenter trial in Canada randomized 301 breast cancer patients between 2008 and 2011 to thrice weekly, supervised exercise during chemotherapy consisting of either a standard dose of 25-30 min of aerobic exercise (STAN; n = 96), a higher dose of 50-60 min of aerobic exercise (HIGH; n = 101), or a combined dose of 50-60 min of aerobic and resistance exercise (COMB; n = 104). The secondary sleep outcomes in the trial were assessed by the Pittsburgh Sleep Quality Index (PSQI) at baseline, twice during chemotherapy, and postchemotherapy. We analyzed the global PSQI and the component scores. Repeated measures analyses of variance indicated that the HIGH group was statistically superior to the STAN group for global sleep quality (mean group difference = -0.90; 95 % CI -0.05 to -1.76; p = 0.039) as well as subjective sleep quality (p = 0.028) and sleep latency (p = 0.049). The COMB group was borderline statistically superior to the STAN group for global sleep quality (mean group difference = -0.76; 95 % CI +0.11 to -1.62; p = 0.085) as well as sleep duration (p = 0.051); and statistically superior for sleep efficiency (p = 0.040), and percentage of poor sleepers (p = 0.045). Compared to a standard volume of aerobic exercise, higher volumes of both aerobic and combined exercise improved some aspects of sleep quality during breast cancer chemotherapy. Exercise may be an attractive option to manage sleep dysfunction in cancer patients during chemotherapy.",

author = "Courneya, {Kerry S.} and Segal, {Roanne J.} and Mackey, {John R.} and Karen Gelmon and Friedenreich, {Christine M.} and Yutaka Yasui and Reid, {Robert D.} and Diana Jespersen and Diane Cook and Carolyn Proulx and Linda Trinh and Dolan, {Lianne B.} and Evyanne Wooding and Forbes, {Cynthia C.} and McKenzie, {Donald C.}",

note = "Funding Information: Acknowledgments This work was supported by a Grant from the Canadian Breast Cancer Research Alliance. KSC and YY are supported by the Canada Research Chairs Program. YY is also supported by the Alberta Innovates-Health Solutions. CMF is supported by a Health Senior Scholar Award from Alberta Innovates-Health Solutions and through the Alberta Cancer Foundation{\textquoteright}s Weekend to End Women{\textquoteright}s Cancers Breast Cancer Chair. LT was supported by a Health Studentship from Alberta Innovates-Health Solutions.",

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doi = "10.1007/s10549-014-2883-0",

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T2 - A multicenter randomized trial

AU - Courneya, Kerry S.

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AU - Mackey, John R.

AU - Gelmon, Karen

AU - Friedenreich, Christine M.

AU - Yasui, Yutaka

AU - Reid, Robert D.

AU - Jespersen, Diana

AU - Cook, Diane

AU - Proulx, Carolyn

AU - Trinh, Linda

AU - Dolan, Lianne B.

AU - Wooding, Evyanne

AU - Forbes, Cynthia C.

AU - McKenzie, Donald C.

N1 - Funding Information: Acknowledgments This work was supported by a Grant from the Canadian Breast Cancer Research Alliance. KSC and YY are supported by the Canada Research Chairs Program. YY is also supported by the Alberta Innovates-Health Solutions. CMF is supported by a Health Senior Scholar Award from Alberta Innovates-Health Solutions and through the Alberta Cancer Foundation’s Weekend to End Women’s Cancers Breast Cancer Chair. LT was supported by a Health Studentship from Alberta Innovates-Health Solutions.

PY - 2014/4

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N2 - To examine the effects of different doses and types of exercise on sleep quality in breast cancer patients receiving chemotherapy. A multicenter trial in Canada randomized 301 breast cancer patients between 2008 and 2011 to thrice weekly, supervised exercise during chemotherapy consisting of either a standard dose of 25-30 min of aerobic exercise (STAN; n = 96), a higher dose of 50-60 min of aerobic exercise (HIGH; n = 101), or a combined dose of 50-60 min of aerobic and resistance exercise (COMB; n = 104). The secondary sleep outcomes in the trial were assessed by the Pittsburgh Sleep Quality Index (PSQI) at baseline, twice during chemotherapy, and postchemotherapy. We analyzed the global PSQI and the component scores. Repeated measures analyses of variance indicated that the HIGH group was statistically superior to the STAN group for global sleep quality (mean group difference = -0.90; 95 % CI -0.05 to -1.76; p = 0.039) as well as subjective sleep quality (p = 0.028) and sleep latency (p = 0.049). The COMB group was borderline statistically superior to the STAN group for global sleep quality (mean group difference = -0.76; 95 % CI +0.11 to -1.62; p = 0.085) as well as sleep duration (p = 0.051); and statistically superior for sleep efficiency (p = 0.040), and percentage of poor sleepers (p = 0.045). Compared to a standard volume of aerobic exercise, higher volumes of both aerobic and combined exercise improved some aspects of sleep quality during breast cancer chemotherapy. Exercise may be an attractive option to manage sleep dysfunction in cancer patients during chemotherapy.

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Effects of exercise dose and type on sleep quality in breast cancer patients receiving chemotherapy: A multicenter randomized trial

Résumé

Note bibliographique

ASJC Scopus Subject Areas

ODD de l’ONU

Accès au document

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