TY - JOUR
T1 - Emulsifiers that enhance susceptibility to virus infection
T2 - Increased virus penetration and reduced interferon response
AU - Lee, S. H.S.
AU - Laltoo, M.
AU - Crocker, J. F.S.
AU - Rozee, K. R.
PY - 1980
Y1 - 1980
N2 - An emulsifier which had an environmental relationship to Reve's syndrome, when used to treated L-929 cultures, was shown to increase the rate of encephalomyocarditis virus penetration and uncoating while having no effect on the attachment of virus or on the replication of infectious ribonucleic acid. This treatment also rendered L-929 cells unable to respond normally to interferon inducers and reversed an already established interferon antiviral state. It is proposed that one or more of these actions result in the cellular enhancement of virus susceptibility.
AB - An emulsifier which had an environmental relationship to Reve's syndrome, when used to treated L-929 cultures, was shown to increase the rate of encephalomyocarditis virus penetration and uncoating while having no effect on the attachment of virus or on the replication of infectious ribonucleic acid. This treatment also rendered L-929 cells unable to respond normally to interferon inducers and reversed an already established interferon antiviral state. It is proposed that one or more of these actions result in the cellular enhancement of virus susceptibility.
UR - http://www.scopus.com/inward/record.url?scp=0019194375&partnerID=8YFLogxK
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U2 - 10.1128/aem.40.4.787-793.1980
DO - 10.1128/aem.40.4.787-793.1980
M3 - Article
C2 - 6158915
AN - SCOPUS:0019194375
SN - 0099-2240
VL - 40
SP - 787
EP - 793
JO - Applied and Environmental Microbiology
JF - Applied and Environmental Microbiology
IS - 4
ER -