Frailty screening in chronic kidney disease: Current perspectives

George Worthen, Karthik Tennankore

Résultat de recherche: Review articleexamen par les pairs

36 Citations (Scopus)

Résumé

Frailty has been defined as a state of increased vulnerability as a consequence of deficit accumulation. Frailty screening has not yet been widely implemented into routine nephrology care. Patients with chronic kidney disease (CKD) are at high risk of being frail, and frailty has been associated with worse outcomes in this population. Standard management of CKD, including initiation of renal replacement therapies, may have decreased benefit or potentially cause harm in the presence of frailty, and a variety of interventions for modifying frailty in the CKD population have been proposed. The optimal means of screening for frailty in patients with kidney disease remains unclear. This review highlights the value of frailty screening in CKD by summarizing the outcomes associated with frailty and exploring proposed changes to the management of frail patients with CKD. Finally, we will propose a framework for how to implement frailty screening into standard nephrology care.

Langue d'origineEnglish
Pages (de-à)229-239
Nombre de pages11
JournalInternational Journal of Nephrology and Renovascular Disease
Volume12
DOI
Statut de publicationPublished - 2019

Note bibliographique

Funding Information:
Dr. Tennankore has received unrestricted grant funding for research from Astellas, Canada, and Otsuka. Dr. Tennankore has participated in Advisory boards for AstraZeneca and Otsuka. The authors report no other conflicts of interest in this work.

Publisher Copyright:
© 2019 Worthen and Tennankore.

ASJC Scopus Subject Areas

  • Nephrology

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