Heterologous adoptive cutaneous anaphylaxis: a method for detecting reaginic antibody formation by cells of the mouse

L. S. Kind, B. Macedo Sobrinho

Résultat de recherche: Articleexamen par les pairs

20 Citations (Scopus)

Résumé

The authors report a method for detecting cells producing reaginic antibody in the mouse. The procedure is based on the finding that spleen, thymus, lymph node, and peritoneal exudate cells from immunized guinea pigs could be transferred to the skin of isologous or homologous guinea pigs with the subsequent detection of antibody at the site of the deposited cells. Presumably antibody from the transferred cells bound to skin mast cells and a typical passive cutaneous anaphylaxis (PCA) reaction resulted upon injection of antigen and Evans blue dye. The technique was termed adoptive cutaneous anaphylaxis (ACA) by Battisto.

Langue d'origineEnglish
Pages (de-à)638-640
Nombre de pages3
JournalJournal of Immunology
Volume111
Numéro de publication2
Statut de publicationPublished - 1973

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Immunology

Empreinte numérique

Plonger dans les sujets de recherche 'Heterologous adoptive cutaneous anaphylaxis: a method for detecting reaginic antibody formation by cells of the mouse'. Ensemble, ils forment une empreinte numérique unique.

Citer