Inhibition of fibroproliferation by pentoxifylline: Activity of metabolite-1 and lack of role of adenosine receptors

Medicine & Life Sciences

• Pentoxifylline 79%
• Purinergic P1 Receptors 74%
• 8-phenyltheophylline 27%
• Platelet-Derived Growth Factor 19%
• Fibroblasts 15%
• Adenosine A2 Receptor Antagonists 13%
• Adenosine A1 Receptor Antagonists 13%
• 1-(5-hydroxyhexyl)-3,7-dimethylxanthine 9%
• Adenosine 8%
• Purinergic P1 Receptor Antagonists 6%
• varespladib methyl 4%

Chemical Compounds

• Pentoxifylline 100%
• Adenosine 57%
• Adenosine A1 Receptor Antagonist 15%
• Adenosine A2 Receptor Antagonist 14%
• Adenosine Receptor Blocking Agent 6%
• Agent Interacting With Transmitter, Hormone or Drug Receptor 4%
• Metabolite 3%
• Additive 2%