Intraductal carcinoma of the prostate is an aggressive form of invasive carcinoma and should be graded

Hemamali Samaratunga, Brett Delahunt, Lars Egevad, John R. Srigley, Athanase Billis, David G. Bostwick, Philippe Camparo, Liang Cheng, David Clouston, James Denham, Bungo Furusato, Arndt Hartmann, Laura Jufe, James Kench, Diane N. Kenwright, Glen Kristiansen, Katia R.M. Leite, Gregory T. MacLennan, Jennifer Merrimen, Holger MochJon Oxley, Chin Chen Pan, Gladell Paner, Jae Ro, Isabell A.M. Sesterhenn, Jonathan Shanks, Michelle Thunders, Toyonori Tsuzuki, Thomas Wheeler, John W. Yaxley, Murali Varma

Résultat de recherche: Review articleexamen par les pairs

32 Citations (Scopus)

Résumé

Infiltration of the prostatic ducts by prostatic adenocarcinoma occurs relatively frequently, being most commonly associated with high grade disease. It is now recognised that intraductal carcinoma of the prostate (IDCP) has an associated poor prognosis and this is reflected in its histological, molecular and immunohistochemical features. The current recommendation of the World Health Organization is that IDCP not be taken into consideration when grading prostate adenocarcinoma. It is apparent that Gleason did not differentiate between IDCP and stromal invasive carcinoma when developing and validating his grading system, and recent studies suggest that the incorporation of IDCP grading into the overall grading of the specimen provides additional prognostic information.

Langue d'origineEnglish
Pages (de-à)192-196
Nombre de pages5
JournalPathology
Volume52
Numéro de publication2
DOI
Statut de publicationPublished - févr. 2020
Publié à l'externeOui

Note bibliographique

Publisher Copyright:
© 2019 Royal College of Pathologists of Australasia

ASJC Scopus Subject Areas

  • Pathology and Forensic Medicine

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