Leukocyte adhesion and the anti-inflammatory effects of leukocyte integrin blockade

T. B. Issekutz

doi:10.1007/978-3-0348-7276-8_9

Leukocyte adhesion and the anti-inflammatory effects of leukocyte integrin blockade

T. B. Issekutz

Medicine

Medicine

Résultat de recherche: Article › examen par les pairs

6 Citations (Scopus)

Résumé

The past several years have produced a dramatic increase in our understanding of the steps involved in the infiltration of leukocytes into inflamed tissues. At least four major families of adhesion molecules: the selectins, sialomucins, integrins, and Ig supergene family CAMs have been identified; and their interactions are being elucidated. The role of the leukocyte β₂ and α₄ integrins and the selective use of these integrins by leukocytes for migration into inflamed tissues in various organs is presented.

Langue d'origine	English
Pages (de-à)	85-96
Nombre de pages	12
Journal	Agents and Actions
Volume	46
Numéro de publication	SUPPL.
DOI	https://doi.org/10.1007/978-3-0348-7276-8_9
Statut de publication	Published - 1995

ASJC Scopus Subject Areas

Toxicology
Pharmacology (medical)

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10.1007/978-3-0348-7276-8_9

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abstract = "The past several years have produced a dramatic increase in our understanding of the steps involved in the infiltration of leukocytes into inflamed tissues. At least four major families of adhesion molecules: the selectins, sialomucins, integrins, and Ig supergene family CAMs have been identified; and their interactions are being elucidated. The role of the leukocyte β2 and α4 integrins and the selective use of these integrins by leukocytes for migration into inflamed tissues in various organs is presented.",

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AB - The past several years have produced a dramatic increase in our understanding of the steps involved in the infiltration of leukocytes into inflamed tissues. At least four major families of adhesion molecules: the selectins, sialomucins, integrins, and Ig supergene family CAMs have been identified; and their interactions are being elucidated. The role of the leukocyte β2 and α4 integrins and the selective use of these integrins by leukocytes for migration into inflamed tissues in various organs is presented.

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Leukocyte adhesion and the anti-inflammatory effects of leukocyte integrin blockade

Résumé

ASJC Scopus Subject Areas

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Autres fichiers et liens

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